IL5

IL5 is a cytokine primarily produced by T-helper cells, particularly Th2 cells, that plays a crucial role in the activation and differentiation of eosinophils. Eosinophils are immune cells involved in the response to parasitic infections and allergic diseases. IL5 enhances eosinophil survival and recruitment to sites of inflammation, particularly in conditions like asthma. It is involved in the pathogenesis of allergic diseases such as rhinitis and bronchial asthma. Therapeutic targeting of IL5 or its receptor has been shown to reduce eosinophil-related inflammation in asthma patients.