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ITGAV & Ad fiber knob
Engineered Antibody Products
Antibody Magnetic Beads
AbPlus
Recombinant Antibody Products
Functional Antibody Products
Formats
Anti-ITGAV & Ad fiber knob Recombinant Antibody Products
- AbPlus™ Anti-ITGAV Magnetic Beads (13C2) (VS-0424-XY160)
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- Target: ITGAV
- Target Species: Human, African Green Monkey, Rabbit, Bovine
- Application: IP, Protein Purification
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- Target: αvβ integrin receptor
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Humanized from Mouse
- Cytokine 1 Species: Human
- Molecule Class: L Kappa; IgG2-IL2
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For Research Use Only. Not For Clinical Use.
Ad fiber knob is expressed in adenovirus.
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
