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    MAGEA6

    Tetramer Products Soluble T Cell Receptor Products

    Anti-MAGEA6 Recombinant Antibody Products

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    For Research Use Only. Not For Clinical Use.


    This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants.
    Protein class

    Cancer-related genes

    Predicted location

    Intracellular

    Single cell type specificity

    Group enriched (Spermatogonia, Spermatocytes)

    Immune cell specificity

    Not detected in immune cells

    Cell line specificity

    Cell line enhanced (GAMG, HMC-1, K-562, OE19, PC-3, SK-BR-3, U-266/70, U-266/84)

    Interaction

    Interacts with TRIM28.

    Molecular function

    Tumor antigen

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