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MAOB
The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine.
Protein class
Enzymes, FDA approved drug targets, Metabolic proteins
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Hepatocytes, Proximal tubular cells, Proximal enterocytes, granulocytes, Cardiomyocytes, Peritubular cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (Hep G2, SiHa)
Interaction
Monomer, homo- or heterodimer (containing two subunits of similar size). Each subunit contains a covalently bound flavin. Enzymatically active as monomer (By similarity).
Molecular function
Oxidoreductase
More Types Infomation
Related Diseases
Amphetamine Addiction
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC
- Mouse Anti-MAOB Recombinant Antibody (clone 8F5) (MOB-2799z)
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA, IHC
-
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IHC
-
- Derivation: Rabbit
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, ELISA
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, WB, IHC
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For Research Use Only. Not For Clinical Use.