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For Research Use Only. Not For Clinical Use.


The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine.
Protein class

Enzymes, FDA approved drug targets, Metabolic proteins

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Hepatocytes, Proximal tubular cells, Proximal enterocytes, granulocytes, Cardiomyocytes, Peritubular cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (Hep G2, SiHa)

Interaction

Monomer, homo- or heterodimer (containing two subunits of similar size). Each subunit contains a covalently bound flavin. Enzymatically active as monomer (By similarity).

Molecular function

Oxidoreductase

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