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NOTCH2 / NOTCH3
Loading...Anti-NOTCH2 / NOTCH3 Products
- Human Anti-NOTCH2 / NOTCH3 Recombinant Antibody (HPAB-AP760-YC) (HPAB-AP760-YC)
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- Species Reactivity: Human, Mouse
- Type: Human IgG2
- Application: FC, Block, Inhib
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- Human Anti-NOTCH2 / NOTCH3 Recombinant Antibody; scFv Fragment (HPAB-AP760-YC-S(P)) (HPAB-AP760-YC-S(P))
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- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: ELISA, FC, Block, FuncS
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- Human Anti-NOTCH2 / NOTCH3 Recombinant Antibody; Fab Fragment (HPAB-AP760-YC-F(E)) (HPAB-AP760-YC-F(E))
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: ELISA, FC, Block, FuncS
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For Research Use Only. Not For Clinical Use.
Background
Neurogenic locus notch homolog protein 2 in humans is encoded by the NOTCH2 gene. Notch 2 is a member of the notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Neurogenic locus notch homolog protein 3 is a protein that in humans is encoded by the NOTCH3 gene. This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development.
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