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OLIG2

Anti-OLIG2 Products
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC, IF, ELISA
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB
- Mouse Anti-OLIG2 Recombinant Antibody (clone 1G11) (VS3-XY1197)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, IHC, ICC
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- Derivation: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: WB, ELISA, IF, IHC
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA, ICC/IF, IHC-P, WB
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: IHC-P, IP, WB
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- Antibody Host: Mouse
- Antibody Reactivity: Human
- Mouse Anti-OLIG2 Monoclonal Antibody (VS7-0425-WR522) (VS7-0425-WR522)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC-P, IF, ICC, ELISA
- Anti-OLIG2 Immunohistochemistry Kit (VS-0325-XY1542)
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- Species Reactivity: Human, Mouse, Rat
- Target: OLIG2
- Application: IHC
- Anti-Human OLIG2 Immunohistochemistry Kit (VS-0525-XY5086)
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- Species Reactivity: Human
- Target: OLIG2
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome.
Protein class
Cancer-related genes, Disease related genes, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Group enriched (Oligodendrocyte precursor cells, Oligodendrocytes)
Immune cell specificity
Immune cell enriched (eosinophil)
Cell line specificity
Cell line enhanced (HMC-1, NB-4, THP-1, WM-115)
Interaction
Interacts with NKX2-2. Interacts with ZNF488.
Molecular function
Developmental protein, DNA-binding
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