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ROR1 & CD3
Receptor tyrosine kinase like orphan receptor 1 (ROR1) is a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.
In immunology, the CD3 (cluster of differentiation 3) T-cell co-receptor is a protein complex and is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These chains associate with a molecule known as the T-cell receptor (TCR) and the ζ-chain to generate an activation signal in T lymphocytes. The TCR, ζ-chain, and CD3 molecules together comprise the TCR complex.
Recombinant Anti-ROR1 × Anti-CD3 Bispecific Antibody (Triplebody) (TRIAB-LC004)
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- Targets: ROR1 & CD3
- Type: Triplebody
- Application: FC
Recombinant Anti-ROR1 × Anti-CD3 Bispecific Antibody (CrossMab) (BSAB-LC002)
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- Targets: ROR1 & CD3
- Type: CrossMab
- Application: FC
Recombinant Anti-ROR1 × Anti-CD3 Bispecific Antibody (Triplebody) (TRIAB-LC005)
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- Targets: ROR1 & CD3
- Type: Triplebody
- Application: FC
Recombinant Anti-ROR1 × Anti-CD3 Bispecific Antibody (F(ab')2) (FAB-LC002)
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- Targets: ROR1 & CD3
- Type: F(ab')2
- Application: FC
Mouse Anti-ROR1 Recombinant Antibody (clone 31C12) (MOB-1937z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA, ICC, IF
Rat Anti-CD3 Recombinant Antibody (clone 17A2) (MOB-0202MC)
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- Species Reactivity: Mouse
- Type: Rat IgG2b, κ
- Application: FC, IHC, IP, Activ, CMCD, Depletion
Human Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-118CL) (TAB-118CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Fab fragment
- Application: ELISA
Afuco™ Anti-Human ROR1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-671CL)
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- Species Reactivity: Human
- Type: ADCC enhanced antibody
Anti-ROR1 (R11) scFv-Fc-Sec ADC (ADC-155LCT)
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- Target: ROR1
- Linker: engineered selenocysteine (Sec) residue
Anti-Human ROR1 Therapeutical Antibody (TAB-698CL)
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- Species Reactivity: Human
- Type: Antibody
Chimeric Anti-Human CD3 Recombinant Antibody Fab Fragment (TAB-0417CL-F(E))
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- Type: Chimeric (mouse/human)
- Application: ELISA, FC, FuncS
Anti-Human CD3 Recombinant Antibody Fab Fragment (OKT3) (TAB-0416CL-F(E))
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- Application: IB, ELISA, FC, FuncS
Anti-Mouse CD3 Recombinant Antibody Fab Fragment (Dow2) (TAB-0365CL-F(E))
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- Application: IP, IB, FuncS
Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-0422CL-S(P)) (TAB-0422CL-S(P))
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Mouse scFv
- Application: ELISA
Human Anti-Human CD3 Recombinant Antibody scFv Fragment (TAB-0532CL-S(P))
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- Type: Human antibody
Anti-Human CD3 Recombinant Antibody scFv Fragment (TAB-0418CL-S(P))
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- Type: Humanized Antibody
- Application: ELISA, FC, FuncS
Chimeric Anti-Human CD3 Recombinant Antibody scFv Fragment (TAB-0417CL-S(P))
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- Type: Chimeric (mouse/human)
- Application: ELISA, FC, FuncS
Anti-Human CD3 Recombinant Antibody scFv Fragment (OKT3) (TAB-0416CL-S(P))
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- Application: IB, ELISA, FC, FuncS
Human Anti-Human CD3 Recombinant Antibody (TAB-0532CL)
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- Type: Human antibody
Anti-Mouse CD3 Recombinant Antibody scFv Fragment (Dow2) (TAB-0365CL-S(P))
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- Application: IP, IB, FuncS
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