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S100A9
Anti-S100A9 Recombinant Antibody Products
- Mouse Anti-S100A9 Antibody (clone IID4B10), mRNA (HPAB-0323-CN-mRNA)
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- Species Reactivity: Human
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- Human Anti-S100A9 Antibody, mRNA (TAB-547CL-mRNA)
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- Species Reactivity: Human
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- Mouse Anti-Mouse S100A9 Recombinant Antibody (CBS104D) (MOB-0810-YJ)
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- Species Reactivity: Mouse
- Type: Mouse IgG1
- Application: IHC-Fr, FuncS, IA, IF, IHC-P, WB
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- Rat Anti-S100A9 Recombinant Antibody (clone 2B10) (VS-0224-XY108)
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- Species Reactivity: Human, Mouse
- Type: Rat IgG2a
- Application: IF, IHC-P, ICC
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- Mouse Anti-S100A9 Recombinant Antibody (clone IID4B10) (HPAB-0323-CN)
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- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, ELISA, IHC
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- Mouse Anti-S100A9 Recombinant Antibody (HPAB-2539LY) (HPAB-2539LY)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, Block, WB
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- Mouse Anti-S100A9 Recombinant Antibody; scFv Fragment (HPAB-2539LY-S(P)) (HPAB-2539LY-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, Block
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- Mouse Anti-S100A9 Recombinant Antibody (clone IID4B10); scFv Fragment (HPAB-0323-CN-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA, IHC
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- Mouse Anti-S100A9 Recombinant Antibody; Fab Fragment (HPAB-2539LY-F(E)) (HPAB-2539LY-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, Block
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- Mouse Anti-S100A9 Recombinant Antibody (clone IID4B10); Fab Fragment (HPAB-0323-CN-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA, IHC
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- Anti-Human S100A9 Recombinant Antibody (TAB-547CL)
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- Species Reactivity: Human
- Type: Antibody
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis. This antimicrobial protein exhibits antifungal and antibacterial activity.
Protein class
Cancer-related genes, Plasma proteins
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (monocytes, Kupffer cells, Basal respiratory cells, Macrophages, Squamous epithelial cells)
Immune cell specificity
Group enriched (neutrophil, classical monocyte)
Cell line specificity
Cell line enriched (SK-BR-3)
Interaction
Homodimer (PubMed:11851337, PubMed:16258195). Preferentially exists as a heterodimer or heterotetramer with S100A8 known as calprotectin (S100A8/A9) (PubMed:16258195, PubMed:17553524, PubMed:19087201, PubMed:19122197, PubMed:8423249, PubMed:9083090, PubMed:25417112). S100A9 interacts with ATP2A2 (By similarity). S100A9 interacts with AGER, and with the heterodimeric complex formed by TLR4 and LY96 in the presence of calcium and/or zinc ions (PubMed:19402754). S100A9 binds quinoline-3-carboxamides in the presence of calcium and/or zinc ions (PubMed:19402754). S100A9 interacts with amyloid-beta protein 40 (PubMed:22457725). Calprotectin (S100A8/9) interacts with CEACAM3 and tubulin filaments in a calcium-dependent manner (PubMed:11708798). Heterotetrameric calprotectin (S100A8/A9) interacts with ANXA6 and associates with tubulin filaments in activated monocytes (PubMed:18786929). Calprotectin (S100A8/9) interacts with NCF2/P67PHOX, RAC1, RAC2, CYBA and CYBB (PubMed:15642721, PubMed:22808130). Calprotectin (S100A8/9) interacts with NOS2 to form the iNOS-S100A8/A9 transnitrosylase complex; induced by LDL(ox) (PubMed:25417112).
Molecular function
Antimicrobial, Antioxidant
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