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SEMA4D
Anti-SEMA4D Recombinant Antibody Products
- CytoStream™ Rat Anti-SEMA4D Recombinant Antibody (clone BMA-12) (VS-0225-XY197)
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- Species Reactivity: Mouse
- Type: Rat IgG2a, lambda
- Application: FC
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For Research Use Only. Not For Clinical Use.
SEMA4D codes for Semaphorin 4D, a protein belonging to the semaphorin family. Semaphorins are a large group of secreted and transmembrane proteins that are involved in a variety of biological processes, including axon guidance, cell migration, and immune regulation. SEMA4D can exist as a transmembrane protein or be proteolytically cleaved to release a soluble form.
Protein class
CD markers, Plasma proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Oligodendrocytes, NK-cells, T-cells, dendritic cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (HDLM-2, HMC-1, JURKAT, MOLT-4)
Interaction
Homodimer (PubMed:20877282). Interacts with PLXNB2 (By similarity). Interacts with PLXNB1 (PubMed:10520995).
Molecular function
Developmental protein, Receptor
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