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SEMA4D

Anti-SEMA4D Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


SEMA4D codes for Semaphorin 4D, a protein belonging to the semaphorin family. Semaphorins are a large group of secreted and transmembrane proteins that are involved in a variety of biological processes, including axon guidance, cell migration, and immune regulation. SEMA4D can exist as a transmembrane protein or be proteolytically cleaved to release a soluble form.
SEMA4D
Protein class

CD markers, Plasma proteins

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Oligodendrocytes, NK-cells, T-cells, dendritic cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (HDLM-2, HMC-1, JURKAT, MOLT-4)

Interaction

Homodimer (PubMed:20877282). Interacts with PLXNB2 (By similarity). Interacts with PLXNB1 (PubMed:10520995).

Molecular function

Developmental protein, Receptor

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