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TNFRSF8
Engineered Antibody Products
Glyco-Engineering Antibody Products
AbPlus
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Anti-TNFRSF8 Recombinant Antibody Products
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- Derivation: Human
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: ELISA, FC, IP, FuncS, IF, Neut
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: Neut, ELISA, IF, IP, FuncS, FC
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- Mouse Anti-TNFRSF8 Agonistic Antibody (VS-0724-XY50) (VS-0724-XY50)
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: WB, FC, Agonistic assays, CyTOF®
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
