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p40

Anti-p40 Products
- Human Anti-p40 Recombinant Antibody (HPAB-N0204-YC) (HPAB-N0204-YC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1, κ
- Application: FuncS, IHC
- Human Anti-p40 Recombinant Antibody; scFv Fragment (HPAB-N0204-YC-S(P)) (HPAB-N0204-YC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human scFv
- Application: FuncS
- Human Anti-p40 Recombinant Antibody; Fab Fragment (HPAB-N0204-YC-F(E)) (HPAB-N0204-YC-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FuncS
- Human Anti-p40 Recombinant Antibody scFv Fragment (HPAB-M0535-YC-S(P)) (HPAB-M0535-YC-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Human Anti-p40 Recombinant Antibody Fab Fragment (HPAB-M0535-YC-F(E)) (HPAB-M0535-YC-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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For Research Use Only. Not For Clinical Use.
Background
Ustekinumab which is marketed under the name Stelara® is a fully human IgGlK antibody which binds to the common p40 subunit of the cytokines IL-12 and IL-23. The antibody-bound cytokines can no longer bind to their cognate receptors and are therefore not able to elicit an inflammatory response in a patient's body.