Human Anti-p40 Recombinant Antibody Fab Fragment (HPAB-M0535-YC-F(E))
CAT#: HPAB-M0535-YC-F(E)
A fully human monoclonal antibody (p40 mAb) directed against human IL-12/23p40 has been shown to be a potent neutralizer of IL-12 and IL-23 function. It has been shown that the p40 mAb binds to the p40 subunit and blocks the binding of both cytokines to their receptors. Because the p40 subunit is shared between IL-12 and IL-23, the detailed interactions between IL-12 and the p40 mAb define an important common neutralizing epitope, which may in turn shed some light on the cytokine-receptor interactions.
Specifications
- Host Species
- Human
- Type
- Human Fab
- Specificity
- Human p40
- Species Reactivity
- Human
- Applications
- ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
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COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "p40"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0535-YC-S(P) | Human Anti-p40 Recombinant Antibody scFv Fragment (HPAB-M0535-YC-S(P)) | ELISA | Human scFv |
| HPAB-N0204-YC-S(P) | Human Anti-p40 Recombinant Antibody; scFv Fragment (HPAB-N0204-YC-S(P)) | FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0204-YC | Human Anti-p40 Recombinant Antibody (HPAB-N0204-YC) | FuncS, IHC | Humanized IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0204-YC-F(E) | Human Anti-p40 Recombinant Antibody; Fab Fragment (HPAB-N0204-YC-F(E)) | FuncS | Humanized Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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