Recombinant Anti-human CALCR Intrabody [(D-Arg)9]
CAT#: IAB-B017(A)
Recombinant anti-CALCR intrabody linked to (D-Arg)9 works within cells to bind intracellur antigen human CALCR, expressed in CHO cells. The intracellular antibody can suppresses the activity of pCRT-1 protein.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SuSa
Immunofluorescent staining of human cell line SuSa shows localization to centriolar satellites, cell junctions & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61428/1968_E2_2_selected.jpg
Normal Tissue
Figure 2 Testis
Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61428/164612_A_6_6.jpg
Normal Tissue
Figure 3 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61428/164612_A_9_4.jpg
Normal Tissue
Figure 4 Kidney
Collecting ducts Staining: Low Intensity: Moderate Quantity: <25% Distal tubules Staining: Medium Intensity: Moderate Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61428/164612_A_7_5.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (RPTEC TERT1, SuSa, T-47d)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000004948-CALCR
❮
❯
Specifications
- Immunogen
- human calcitonin receptor
- Host Species
- mouse
- Type
- scFv-(D-Arg)9
- Cell Penetrating Peptide
- (D-Arg)9
It has been proven that polyarginine peptides composed of nine arginine amino acids (Arg-9) are able to translocate across cells very efficiently. This raises the question if molecular dynamics simulations would show a similar pathway for this highly hydrophilic and charged peptide as predicted for the Tat peptide. The simplicity of Arg-9 over other CPPs also helps isolate the role of the Arg sidechain on the translocation without the effect of other sidechains. Therefore, in this work we study computationally the translocation of Arg-9 through a lipid bilayer and show that the translocation mechanism is the same as for the Tat peptide.
- Species Reactivity
- human
- Applications
- Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Immunofluorescence; Neutralization; Functional studies
Product Property
- Purity
- >95%, by SDS-PAGE, under reducing conditions
- Storage
- Can be stored at 4°C. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles.
Target
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for IAB-B017(A). Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "CALCR"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B017(G) | Recombinant Anti-human CALCR Intrabody [+36 GFP] | ELISA, Neut, FuncS | scFv-(+36GFP) |
| IAB-B017(T) | Recombinant Anti-human CALCR Intrabody [Tat] | PCA, WB, FuncS | scFv-Tat |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1471CL | Mouse Anti-CALCR Recombinant Antibody (TAB-1471CL) | FC, ELISA, IHC | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1472CL | Mouse Anti-CALCR Recombinant Antibody (TAB-1472CL) | IF, FC, ELISA, IHC | Mouse IgG2A |
| TAB-1473CL | Mouse Anti-CALCR Recombinant Antibody (TAB-1473CL) | FC, ELISA, IHC | Mouse IgG2A |
| TAB-1471CL-F(E) | Mouse Anti-CALCR Recombinant Antibody; Fab Fragment (TAB-1471CL-F(E)) | FC, ELISA, IHC | Mouse Fab |
| TAB-1472CL-F(E) | Mouse Anti-CALCR Recombinant Antibody; Fab Fragment (TAB-1472CL-F(E)) | IF, FC, ELISA, IHC | Mouse Fab |
| TAB-1473CL-F(E) | Mouse Anti-CALCR Recombinant Antibody; Fab Fragment (TAB-1473CL-F(E)) | FC, ELISA, IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1951MZ | Mouse Anti-CALCR Recombinant Antibody (clone 27/00-3G2) | ELISA, IHC-P, WB | Mouse IgG1 |
| PABS-0272 | Camelid Anti-CALCR Recombinant Antibody (clone nb35) | ELISA | Camelid VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC246 | Recombinant Anti-CALCR Vesicular Antibody, EV Displayed (VS-0425-YC246) | ELISA, FC, Cell-uptake |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: WB, IF, IP, Neut, FuncS, ELISA, FC
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: FuncS, IF, Neut, ELISA, FC, IP, WB
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: ELISA, WB, BLI, SPR
Application: WB, IF, FuncS
Application: WB, ELISA, FC, IHC, IP
Application: FC, IHC, Cyt, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
