Anti-Human CD22 Recombinant Antibody (CD22.2) (CAT#: TAB-1722CL)

This monoclonal antibody that specifically binds to CD22 with high affinity can be used for detecting CD22, as well as for treating various cancers and inflammatory and autoimmune disorders.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Tested Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
ELISA

Figure 1 is a graph shows CD22 ECD binding by anti-CD22 recombinant human antibodies CD22.1 and CD22.2 as compared to that of the 19A3 parent human antibody.

Figure 1 is a graph shows CD22 ECD binding by anti-CD22 recombinant human antibodies CD22.1 and CD22.2 as compared to that of the 19A3 parent human antibody.

FC

Figure 2 is a graph shows binding of CD22 expressed on the surface of CHO cells by the by anti-CD22 recombinant human antibodies CD22.1 and CD22.2.

Figure 2 is a graph shows binding of CD22 expressed on the surface of CHO cells by the by anti-CD22 recombinant human antibodies CD22.1 and CD22.2.

FC

Figure 3 is a graph shows binding of CD22 expressed on the surface of Raji cells by the by anti-CD22 recombinant human antibodies CD22.1 and CD22.2.

Figure 3 is a graph shows binding of CD22 expressed on the surface of Raji cells by the by anti-CD22 recombinant human antibodies CD22.1 and CD22.2.

ELISA

Figure 4 is a bar graph shows binding of the CD22 ECD amino-terminal domains 1 and 2 by anti-CD22 antibodies 12C5, 19A3, 16F7 and 23C6, and by recombinant human antibodies CD22.1 and CD22.2.

Figure 4 is a bar graph shows binding of the CD22 ECD amino-terminal domains 1 and 2 by anti-CD22 antibodies 12C5, 19A3, 16F7 and 23C6, and by recombinant human antibodies CD22.1 and CD22.2.

FuncS

Figure 5 shows the in-vivo effect of antibody-drug conjugates CD22.1-Cytotoxin A and CD22.2-Cytotoxin A on Raji-cell tumor size in SCID mice.

Figure 5 shows the in-vivo effect of antibody-drug conjugates CD22.1-Cytotoxin A and CD22.2-Cytotoxin A on Raji-cell tumor size in SCID mice.


Specifications

  • Host Species
  • Human
  • Type
  • Human antibody
  • Specificity
  • Human
  • Clone
  • CD22.2
  • Applications
  • ELISA, FC, FuncS
  • Related Disease
  • Cancers and inflammatory and autoimmune disorders

Applications

  • Application Notes
  • This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Flow Cytotoxicityometry, Functional Assay.

Target

  • Alternative Names
  • CD22; CD22 molecule; SIGLEC2; SIGLEC-2; B-cell receptor CD22; BL-CAM; CD22 antigen; T-cell surface antigen Leu-14; B-lymphocyte cell adhesion molecule; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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