Afuco™ Anti-Human DKK1 ADCC Recombinant Antibody (BHQ880), ADCC Enhanced (CAT#: AFC-202CL)
Anti-DKK1 ADCC Enhanced Antibody (BHQ880) is an ADCC enhanced antibody produced by our Afuco™ platform. BHQ880 is a human neutralizing IgG1 anti-DKK1 monoclonal antibody, that is being investigated for its impact on multiple myeloma-related bone disease and as an agent with potential anti-myeloma activity. BHQ880 in combination with zoledronic acid and anti-myeloma therapy was well tolerated and demonstrated potential clinical activity in patients with relapsed or refractory multiple myeloma.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+, CACO-2, fHDF/TERT166)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000107984-DKK1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000107984-DKK1
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Bone-related Diseases; Multiple Myeloma
Product Property
- Purity
- >95%, by SDS-PAGE, under reducing conditions
- Storage
- ≥1 year at -20°C. If the reconstituted antibody cannot be used within two weeks, it should be aliquoted into smaller vials and stored at -20°C
Target
- Alternative Names
- DKK1; dickkopf WNT signaling pathway inhibitor 1; SK; DKK-1; dickkopf-related protein 1; hDkk-1; dickkopf-1 like; dickkopf 1 homolog; dickkopf-like protein 1; dickkopf related protein-1
- Gene ID
- 22943
- UniProt ID
- I1W660
Related Resources
Canonical Wnt Signaling Pathway
Non-Canonical Wnt Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-192MZ | Anti-Mouse DKK1 Recombinant Antibody (JC18) | ELISA, FuncS | |
| TAB-194MZ | Mouse Anti-DKK1 Recombinant Antibody (TAB-194MZ) | ELISA | Mouse IgG |
| TAB-196MZ | Rat Anti-DKK1 Recombinant Antibody (TAB-196MZ) | FuncS | Rat IgG |
| TAB-192MZ-S(P) | Anti-Mouse DKK1 Recombinant Antibody scFv Fragment (JC18) | ELISA | |
| TAB-194MZ-S(P) | Mouse Anti-DKK1 Recombinant Antibody; scFv Fragment (TAB-194MZ-S(P)) | ELISA | Mouse scFv |
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