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    Human Anti-JAG1 Recombinant Antibody Fab Fragment (PFBL-312) (CAT#: PFBL-312)

    Recombinant Human Antibody is capable of binding to Protein jagged-1, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-Protein jagged-1 fab and CH1-3 region of human fab and a light chain (LC) encoding VL from anti-Protein jagged-1 fab and CL of human light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-251 MG
    Figure 1 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & the Golgi apparatus.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/10343/if_selected.jpg
    Normal Tissue
    Figure 2 IHC staining of human kidney
    Figure 2 IHC staining of human kidney
    (Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/21555/48721_A_8_5_selected.jpg
    Figure 3 IHC staining of human gall bladder
    Figure 3 IHC staining of human gall bladder
    (Immunohistochemical staining of human gall bladder shows strong membranous and cytoplasmic positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/10343/ihc_selected.jpg
    Figure 4 Cerebral cortex
    Figure 4 Cerebral cortex
    (Endothelial cells
    Staining: Low
    Intensity: Weak
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Neuropil
    Staining: Low
    Intensity: Weak
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/10343/25743_B_7_5.jpg
    Figure 5 Colon
    Figure 5 Colon
    (Endothelial cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Glandular cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Peripheral nerve/ganglion
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/10343/25743_A_9_3.jpg
    Figure 6 Liver
    Figure 6 Liver
    (Hepatocytes
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/10343/25743_A_8_4.jpg
    Figure 7 Gallbladder
    Figure 7 Gallbladder
    (Glandular cells
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/10343/25743_A_6_4.jpg
    Figure 8 Testis
    Figure 8 Testis
    (Leydig cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/10343/25743_A_5_6.jpg
    Figure 9 Lymph node
    Figure 9 Lymph node
    (Germinal center cells
    Staining: Low
    Intensity: Moderate
    Quantity: <25%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining: Low
    Intensity: Moderate
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/10343/25743_A_9_8.jpg
    RNA Expression
    Figure 10 RNA cell line category: Cell line enhanced (HBEC3-KT, hTERT-HME1, U-251 MG)
    Figure 10 RNA cell line category: Cell line enhanced (HBEC3-KT, hTERT-HME1, U-251 MG)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000101384-JAG1

    Specifications

    • Immunogen
    • Human jagged 1
    • Host Species
    • Human
    • Derivation
    • Human
    • Type
    • Human Fab
    • Specificity
    • Human JAG1
    • Species Reactivity
    • Human
    • Applications
    • WB, Neut, FuncS

    Product Property

    • Purity
    • >95% as determined by SDS-PAGE
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • PBS
    • Preservative
    • No preservatives
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Target

    • Alternative Names
    • JAG1; jagged 1; AGS; AHD; AWS; HJ1; CD339; JAGL1; protein jagged-1

    Related Resources

    • Related Signaling Pathways

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

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    CAT Product Name Application Type
    PABL-312 Human Anti-JAG1 Recombinant Antibody (PABL-312) IB, IF, IHC Human IgG
    PABL-622 Human Anti-JAG1 Recombinant Antibody WB, ELISA, FuncS Human IgG
    HPAB-0942LY Human Anti-JAG1 Recombinant Antibody (HPAB-0942LY) ELISA Human IgG
    HPAB-0943LY Human Anti-JAG1 Recombinant Antibody (HPAB-0943LY) ELISA Human IgG
    HPAB-0944LY Human Anti-JAG1 Recombinant Antibody (HPAB-0944LY) ELISA Human IgG

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