Anti-ganglioside GM2 monoclonal antibody BIW-8962 (Gly-013CL)

A humanized anti-ganglioside GM2 (GM2) monoclonal antibody with potential antineoplastic and immunomodulating activities. Upon administration, anti-ganglioside GM2 monoclonal antibody BIW-8962 may activate an antibody dependent cellular cytotoxicity (ADCC) against GM2-expressing tumor cells. GM2 is a tumor associated antigen (TAA) overexpressed on the surface of many cancer cells, such as multiple myeloma (MM) cells and neuroblastoma cells.      

Humanized monoclonal antibody
Mechanism of Action
G(M2) ganglioside inhibitors
Alternative Names
Anti-GM2 humanised antibody; BIW-8962; anti-GM2 monoclonal antibody BIW-8962

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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