Anti-ganglioside GM2 monoclonal antibody BIW-8962 (CAT#: Gly-013CL)
A humanized anti-ganglioside GM2 (GM2) monoclonal antibody with potential antineoplastic and immunomodulating activities. Upon administration, anti-ganglioside GM2 monoclonal antibody BIW-8962 may activate an antibody dependent cellular cytotoxicity (ADCC) against GM2-expressing tumor cells. GM2 is a tumor associated antigen (TAA) overexpressed on the surface of many cancer cells, such as multiple myeloma (MM) cells and neuroblastoma cells.
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Specifications
- Type
- Humanized monoclonal antibody
- Class
- Antineoplastics; Monoclonal antibodies
- Mechanism of action
- G(M2) ganglioside inhibitors
References
- Synonyms
- Anti-GM2 humanised antibody; BIW-8962; anti-GM2 monoclonal antibody BIW-8962
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Fab Fragment Antibody
| CAT | Product Name | Application | Type |
| MOB-406-F(E) | Recombinant Anti-GM2 Antibody Fab Fragment | IP, FuncS | Fab |
| MHH-406-F(E) | Recombinant Human Anti-GM2 Antibody Fab Fragment | ELISA, IP, FuncS | Fab |
| HPAB-S0039-YC-F(E) | Human Anti-GM2 Recombinant Antibody (clone KM8966); Fab Fragment | ELISA, ADCC | Human Fab |
| HPAB-S0040-YC-F(E) | Human Anti-GM2 Recombinant Antibody (clone KM8967); Fab Fragment | ELISA, ADCC | Human Fab |
| MOB-102YJL-F(E) | Mouse Anti-GM2 Recombinant Antibody (clone KM796); Fab Fragment | ELISA, ADCC, CDC, FuncS | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
| MOB-406-S(P) | Recombinant Anti-GM2 Antibody scFv Fragment | IF, FC, Biosensors, FuncS | scFv |
| HPAB-S0039-YC-S(P) | Human Anti-GM2 Recombinant Antibody (clone KM8966); scFv Fragment | ELISA, ADCC | Human scFv |
| HPAB-S0040-YC-S(P) | Human Anti-GM2 Recombinant Antibody (clone KM8967); scFv Fragment | ELISA, ADCC | Human scFv |
| FAMAB-0054WJ-S(P) | Human Anti-GM2 Recombinant Antibody (clone L55-81); scFv Fragment | WB | Human scFv |
| MOB-102YJL-S(P) | Mouse Anti-GM2 Recombinant Antibody (clone KM796); scFv Fragment | ELISA, ADCC, CDC, FuncS | Mouse scFv |
Humanized Antibody
| CAT | Product Name | Application | Type |
| TAB-320CL | Anti-Human GM2 Recombinant Antibody (BIW-8962) | FC, FuncS, IF | Antibody |
Mouse Antibody
| CAT | Product Name | Application | Type |
| TAB-169CT | Anti-Human GM2 (Monosialo-GM2) Recombinant Antibody (DMF10.62.3) | ELISA, FC, IHC | |
| TAB-170CT | Anti-Human GM2 (Monosialo-GM2) Recombinant Antibody (DMF10.167.4) | IHC, FC, WB, Inhib, IF, ELISA | |
| TAB-169CT-S(P) | Anti-Human GM2 (Monosialo-GM2) Recombinant Antibody scFv Fragment (DMF10.62.3) | ELISA, FC, IHC | |
| TAB-169CT-F(E) | Anti-Human GM2 (Monosialo-GM2) Recombinant Antibody Fab Fragment (DMF10.62.3) | ELISA, FC, IHC | |
| TAB-170CT-F(E) | Anti-Human GM2 (Monosialo-GM2) Recombinant Antibody Fab Fragment (DMF10.167.4) | ELISA, FC, IHC |
Recombinant Antibody
| CAT | Product Name | Application | Type |
| HPAB-S0039-YC | Human Anti-GM2 Recombinant Antibody (clone KM8966) | ELISA, ADCC | Human IgG |
| HPAB-S0040-YC | Human Anti-GM2 Recombinant Antibody (clone KM8967) | ELISA, ADCC | Human IgG |
| FAMAB-1396CQ | Mouse Anti-GM2 Recombinant Antibody (clone E1) | ELISA, IHC | Mouse IgG1 |
| MOB-102YJL | Mouse Anti-GM2 Recombinant Antibody (clone KM796) | ELISA, ADCC, CDC, FuncS | Mouse IgG1 |
| HPAB-A1367-YJ | Human Anti-GM2 Recombinant Antibody (clone KM966) | ELISA, IF, ADCC | Chimeric (mouse/human) IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
* Abbreviations
3D IHC3D Immunohistochemistry
ActivActivation
AgonistAgonist
ApopApoptosis
BABioassay
BIBioimaging
BlockBlocking
Cell ScreeningCell Screening
SeparationCell Separation
ChIPChromatin Immunoprecipitation
CMCDComplement Mediated Cell Depletion
CostimCostimulation
CytCytotoxicity
DepletionDepletion
DBDot Blot
EMElectron Microscopy
ELISAEnzyme-linked Immunosorbent Assay
ELISPOTEnzyme-linked Immunosorbent Spot
FCFlow Cytometry
FuncSFunctional Assay
GSGel Super Shift Assay
HAHemagglutination
IAImmunoassay
IBImmunoblotting
ICCImmunocytochemistry
IDImmunodiffusion
IFImmunofluorescence
IHCImmunohistochemistry
IHC-FrImmunohistochemistry-Frozen
IHC-PImmunohistochemistry-Paraffin
REImmunohistology - Resin Sections
IPImmunoprecipitation
IRMAImmunoradiometric Assay
SHIn situ hybridization
InhibInhibition
ICFCIntracellular Staining for Flow Cytometry
KO/KD-WBKnockout/Knockdown target confirmation by Western Blot
Live cell imagingLive cell imaging
CyTOF®Mass Cytometry
MeDIPMethylated DNA Immunoprecipitation
MultiplexMultiplex bead-based assay
NeutNeutralization
PPProtein Purification
PGProteogenomics
RIRadial Immunodiffusion
RIARadioimmunoassay
StimStimulation
SPRSurface Plasmon Resonance
TCTissue Culture
TBTurbidimetry
WBWestern Blot
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