Anti-ganglioside GM2 monoclonal antibody BIW-8962 (CAT#: Gly-013CL)

A humanized anti-ganglioside GM2 (GM2) monoclonal antibody with potential antineoplastic and immunomodulating activities. Upon administration, anti-ganglioside GM2 monoclonal antibody BIW-8962 may activate an antibody dependent cellular cytotoxicity (ADCC) against GM2-expressing tumor cells. GM2 is a tumor associated antigen (TAA) overexpressed on the surface of many cancer cells, such as multiple myeloma (MM) cells and neuroblastoma cells.

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Specifications

  • Type
  • Humanized monoclonal antibody
  • Class
  • Antineoplastics; Monoclonal antibodies
  • Mechanism of action
  • G(M2) ganglioside inhibitors

References

  • Synonyms
  • Anti-GM2 humanised antibody; BIW-8962; anti-GM2 monoclonal antibody BIW-8962

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See other products for "GM2"

Fab Fragment Antibody

CAT Product Name Application Type
MOB-406-F(E) Recombinant Anti-GM2 Antibody Fab Fragment IP, FuncS Fab
MHH-406-F(E) Recombinant Human Anti-GM2 Antibody Fab Fragment ELISA, IP, FuncS Fab
HPAB-S0039-YC-F(E) Human Anti-GM2 Recombinant Antibody (clone KM8966); Fab Fragment ELISA, ADCC Human Fab
HPAB-S0040-YC-F(E) Human Anti-GM2 Recombinant Antibody (clone KM8967); Fab Fragment ELISA, ADCC Human Fab
MOB-102YJL-F(E) Mouse Anti-GM2 Recombinant Antibody (clone KM796); Fab Fragment ELISA, ADCC, CDC, FuncS Mouse Fab

scFv Fragment Antibody

CAT Product Name Application Type
MOB-406-S(P) Recombinant Anti-GM2 Antibody scFv Fragment IF, FC, Biosensors, FuncS scFv
HPAB-S0039-YC-S(P) Human Anti-GM2 Recombinant Antibody (clone KM8966); scFv Fragment ELISA, ADCC Human scFv
HPAB-S0040-YC-S(P) Human Anti-GM2 Recombinant Antibody (clone KM8967); scFv Fragment ELISA, ADCC Human scFv
FAMAB-0054WJ-S(P) Human Anti-GM2 Recombinant Antibody (clone L55-81); scFv Fragment WB Human scFv
MOB-102YJL-S(P) Mouse Anti-GM2 Recombinant Antibody (clone KM796); scFv Fragment ELISA, ADCC, CDC, FuncS Mouse scFv

Humanized Antibody

CAT Product Name Application Type
TAB-320CL Anti-Human GM2 Recombinant Antibody (BIW-8962) FC, FuncS, IF Antibody

Mouse Antibody

CAT Product Name Application Type
TAB-169CT Anti-Human GM2 (Monosialo-GM2) Recombinant Antibody (DMF10.62.3) ELISA, FC, IHC
TAB-170CT Anti-Human GM2 (Monosialo-GM2) Recombinant Antibody (DMF10.167.4) IHC, FC, WB, Inhib, IF, ELISA
TAB-169CT-S(P) Anti-Human GM2 (Monosialo-GM2) Recombinant Antibody scFv Fragment (DMF10.62.3) ELISA, FC, IHC
TAB-169CT-F(E) Anti-Human GM2 (Monosialo-GM2) Recombinant Antibody Fab Fragment (DMF10.62.3) ELISA, FC, IHC
TAB-170CT-F(E) Anti-Human GM2 (Monosialo-GM2) Recombinant Antibody Fab Fragment (DMF10.167.4) ELISA, FC, IHC

Recombinant Antibody

CAT Product Name Application Type
HPAB-S0039-YC Human Anti-GM2 Recombinant Antibody (clone KM8966) ELISA, ADCC Human IgG
HPAB-S0040-YC Human Anti-GM2 Recombinant Antibody (clone KM8967) ELISA, ADCC Human IgG
FAMAB-1396CQ Mouse Anti-GM2 Recombinant Antibody (clone E1) ELISA, IHC Mouse IgG1
MOB-102YJL Mouse Anti-GM2 Recombinant Antibody (clone KM796) ELISA, ADCC, CDC, FuncS Mouse IgG1
HPAB-A1367-YJ Human Anti-GM2 Recombinant Antibody (clone KM966) ELISA, IF, ADCC Chimeric (mouse/human) IgG1

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

* Abbreviations
3D IHC3D Immunohistochemistry
ActivActivation
AgonistAgonist
ApopApoptosis
BABioassay
BIBioimaging
BlockBlocking
Cell ScreeningCell Screening
SeparationCell Separation
ChIPChromatin Immunoprecipitation
CMCDComplement Mediated Cell Depletion
CostimCostimulation
CytCytotoxicity
DepletionDepletion
DBDot Blot
EMElectron Microscopy
ELISAEnzyme-linked Immunosorbent Assay
ELISPOTEnzyme-linked Immunosorbent Spot
FCFlow Cytometry
FuncSFunctional Assay
GSGel Super Shift Assay
HAHemagglutination
IAImmunoassay
IBImmunoblotting
ICCImmunocytochemistry
IDImmunodiffusion
IFImmunofluorescence
IHCImmunohistochemistry
IHC-FrImmunohistochemistry-Frozen
IHC-PImmunohistochemistry-Paraffin
REImmunohistology - Resin Sections
IPImmunoprecipitation
IRMAImmunoradiometric Assay
SHIn situ hybridization
InhibInhibition
ICFCIntracellular Staining for Flow Cytometry
KO/KD-WBKnockout/Knockdown target confirmation by Western Blot
Live cell imagingLive cell imaging
CyTOF®Mass Cytometry
MeDIPMethylated DNA Immunoprecipitation
MultiplexMultiplex bead-based assay
NeutNeutralization
PPProtein Purification
PGProteogenomics
RIRadial Immunodiffusion
RIARadioimmunoassay
StimStimulation
SPRSurface Plasmon Resonance
TCTissue Culture
TBTurbidimetry
WBWestern Blot

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