Anti-ganglioside GM2 monoclonal antibody BIW-8962 (CAT#: Gly-013CL)
A humanized anti-ganglioside GM2 (GM2) monoclonal antibody with potential antineoplastic and immunomodulating activities. Upon administration, anti-ganglioside GM2 monoclonal antibody BIW-8962 may activate an antibody dependent cellular cytotoxicity (ADCC) against GM2-expressing tumor cells. GM2 is a tumor associated antigen (TAA) overexpressed on the surface of many cancer cells, such as multiple myeloma (MM) cells and neuroblastoma cells.
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Specifications
- Type
- Humanized monoclonal antibody
- Class
- Antineoplastics; Monoclonal antibodies
- Mechanism of action
- G(M2) ganglioside inhibitors
References
- Synonyms
- Anti-GM2 humanised antibody; BIW-8962; anti-GM2 monoclonal antibody BIW-8962
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Recombinant Antibody
Fab Fragment Antibody
scFv Fragment Antibody
Humanized Antibody
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-406 | Recombinant Anti-GM2 Antibody | ELISA, WB, IF, FuncS | IgG |
| HPAB-S0039-YC | Human Anti-GM2 Recombinant Antibody (clone KM8966) | ELISA, ADCC | Human IgG |
| HPAB-S0040-YC | Human Anti-GM2 Recombinant Antibody (clone KM8967) | ELISA, ADCC | Human IgG |
| FAMAB-0054WJ | Human Anti-GM2 Recombinant Antibody (clone L55-81) | WB, ELISA, Cyt, IHC | Human IgM |
| FAMAB-1396CQ | Mouse Anti-GM2 Recombinant Antibody (clone E1) | ELISA, IHC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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