Mouse Anti-ADGRG1 Recombinant Antibody (VS3-FY2621)
CAT#: VS3-FY2621
This anti-ADGRG1 antibody is a mouse recombinant monoclonal antibody that is specifically created to bind GPR56. The calculated molecular weight of the antigen is 77.7 kDa. It shows capability of cross-reacting with human. This monoclonal antibody is potential for conducting research on Cortical Dysplasia, Complex, With Other Brain Malformations 14A and Cortical Dysplasia, Complex, With Other Brain Malformations 14B. This monoclonal antibody can be used in Immunohistochemistry, Flow cytometry, ELISA.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Adhesion G protein-coupled receptor G1 of human
- Species Reactivity
- Human
- Applications
- IHC, FC, ELISA
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 77.7 kDa.
- Related Disease
- Cortical Dysplasia, Complex, With Other Brain Malformations 14A and Cortical Dysplasia, Complex, With Other Brain Malformations 14B
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Immunohistochemistry: 1/50-1/200
Flow cytometry: 1/50-1/200
ELISA: 1/1000-1/10000
Target
- Alternative Names
- Adhesion G Protein-Coupled Receptor G1; G Protein-Coupled Receptor 56; G-Protein Coupled Receptor 56; TM7LN4; TM7XN1; GPR56; 7-Transmembrane Protein With No EGF-Like N-Terminal Domains-1
- Gene ID
- 9289
- Sequence Similarities
- Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Autoproteolytically cleaved into 2 fragments; the large extracellular N-terminal fragment (ADGRG1 NT) and the membrane-bound C-terminal fragment (ADGRG1 CT) predominantly remain associated and non-covalently linked.
Shedding to yield the secreted ADGRG1 N-terminal fragment seems to involve metalloprotease(s).
N-glycosylated.
Contains sialic acid residues.
Ubiquitinated.
- Protein Refseq
- XP_005256294.1; XP_005256295.1; XP_005256296.1; XP_005256297.1; XP_005256298.1
- Function
- Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells.
Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination (By similarity).
Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12 (PubMed:22238662).
Plays a role in the maintenance of hematopoietic stem cells and/or leukemia stem cells in bone marrow niche (By similarity).
Plays a critical role in cancer progression by inhibiting VEGFA production threreby inhibiting angiogenesis through a signaling pathway mediated by PRKCA (PubMed:16757564, 21724588).
Plays an essential role in testis development (By similarity).
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS3-FY2621. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "ADGRG1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-QX23 | Mouse Anti-ADGRG1 Recombinant Antibody (clone 1443CT377.65.29) | WB, ICC | Mouse IgG1 |
| VS3-WK1233 | Mouse Anti-ADGRG1 Recombinant Antibody (VS3-WK1233) | IF, WB | Mouse IgG1, κ |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: WB, IF, IP, Neut, FuncS, ELISA, FC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
Application: Neut, Inhib, FC, ELISA
Application: Block, IP, IF, FC
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, FC, IF, IHC, WB
Application: FC
Application: ELISA, IHC, WB
Application: ELISA, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
