Afuco™ Anti-ERBB2 ADCC Recombinant Antibody (Pertuzumab), ADCC Enhanced (CAT#: AFC-TAB-053)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to ERBB2. Pertuzumab (also called 2C4, trade name pertuzumab) is a monoclonal antibody. The first of its class in a line of agents called "HER dimerization inhibitors". By binding to HER2, it inhibits the dimerization of HER2 with other HER receptors, which is hypothesized to result in slowed tumor growth.
Specific Inquiry
SDS-PAGE
Figure 1 Anti-Human ERBB2 Recombinant Antibody (AFC-TAB-053) in SDS-PAGE
SDS-PAGE analysis of AFC-TAB-053 in β-mercaptoethanol-reduced (Lane left) and non-reduced (Lane right) conditions.
ELISA
Figure 2 Anti-Human ERBB2 Recombinant Antibody (AFC-TAB-053) in ELISA
ELISA analysis of AFC-TAB-053 was performed by coating with human ERBB2 protein (His tag).
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Clone
- Pertuzumab
- Applications
- FuncS, IF, Neut, ELISA, FC, IP
- Conjugate
- Unconjugated
- Trade name
- Pertuzumab, Omnitarg
- Generic Name
- Pertuzumab
- Related Disease
- Prostate cancers
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Pertuzumab; pertuzumab, Omnitarg; 380610-27-5; rhuMAb 2C4; RG1273; pertuzumab; 2C4; pertuzumab; Omnitarg; ERBB2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian);
- Gene ID
- 2064
- UniProt ID
- P04626
Related Resources
Bladder Cancer
Non-small Cell Lung Cancer
ErbB Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Pertuzumab"
Anti-Human ERBB2 Recombinant Antibody (Pertuzumab)Recombinant monoclonal antibody to ERBB2. Pertuzumab (also called 2C4, trade name pertuzumab) is a monoclonal antibody. The first of its class in a line of agents called "HER dimerization inhibitors". By binding to HER2, it inhibits the dimerization of HER2 with other HER receptors, which is hypothesized to result in slowed tumor growth.
See other products for "Clone pertuzumab"
See other products for "ERBB2"
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Please select product type
Single-domain Antibody
Intrabody
Chimeric Antibody
Humanized Antibody
Immunotoxin
Mouse Antibody
Human Antibody
Fab Glycosylation
Fc Glycosylation
Deglycosylated Antibody (Non-glycosylated IgGs)
Chicken IgY Antibody
Blocking Antibody
Rabbit Monoclonal Antibody
Fab Fragment Antibody
ADCC Enhanced Antibody
MHC Tetramer for Cancer
Recombinant Antibody
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-059 | Recombinant Anti-Human ERBB2 VHH Single Domain Antibody | IHC, FC, CA, FuncS | Llama VHH |
| PNBL-066 | Recombinant Anti-HER2 VHH Single Domain Antibody (PNBL-066) | SPR | Llama VHH |
| PNBL-067 | Recombinant Anti-HER2 VHH Single Domain Antibody (PNBL-067) | SPR | Llama VHH |
| PNBL-069 | Recombinant Anti-HER2 VHH Single Domain Antibody (PNBL-069) | ELISA | Llama VHH |
| HPAB-1026WJ | Recombinant Camelid Anti-ERBB2 Single Domain Antibody | ELISA | Camelid VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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