Recombinant monoclonal antibody strongly binds to human the immunoglobulin–like ectodomains (residues1-185) of glycoprotein VI, also called D1D2. 1C3 is a human monoclonal antibody that can be useful in the treatment of damage to blood vessels.
Figure 1 Binding of scFvs to GPVI in ELISA.
Wells were precoated with BSA-N9A, and then buffer alone (plate) or buffer containing CaM-tagged antigens (hD1D2, irrelevant scFv, hD1, hD2, mD1D2) was added, capturing them to the solid phase.
Smethurst, P. A., Joutsi-Korhonen, L., O'Connor, M. N., Wilson, E., Jennings, N. S., Garner, S. F., Zhang, Y., Knight, C. G., Dafforn, T. R., Buckle, A., IJsseldijk, M. J., De Groot, P. G., Watkins, N. A., Farndale, R. W., & Ouwehand, W. H. (2004). Identification of the primary collagen-binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody. Blood, 103(3), 903–911.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-003CT | Anti-Human GPVI Recombinant Antibody (1C3) | Funcs, ELISA, Inhib, FC | Human antibody |
TAB-003CT-S(P) | Anti-Human GPVI Recombinant Antibody scFv Fragment (1C3) | Funcs, ELISA, Inhib, FC | Human antibody |
TAB-003CT-F(E) | Anti-Human GPVI Recombinant Antibody Fab Fragment (1C3) | ELISA, Inhibition, FC | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-005CT | Mouse Anti-GP6 Recombinant Antibody (TAB-005CT) | WB, ELISA, Block | Mouse IgG1, κ |
TAB-005CT-S(P) | Mouse Anti-GP6 Recombinant Antibody; scFv Fragment (TAB-005CT-S(P)) | WB, ELISA, Block | Mouse scFv |
TAB-005CT-F(E) | Mouse Anti-GP6 Recombinant Antibody; Fab Fragment (TAB-005CT-F(E)) | WB, ELISA, Block | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1483 | Hi-Affi™ Rabbit Anti-GP6 Recombinant Antibody (clone DS1483AB) | WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0002-CN | Human Anti-GP6 Recombinant Antibody (HPAB-0002-CN) | FC, WB | Humanized IgG |
HPAB-0003-CN | Human Anti-GP6 Recombinant Antibody (HPAB-0003-CN) | FC, WB | Humanized IgG |
HPAB-0004-CN | Mouse Anti-GP6 Recombinant Antibody (HPAB-0004-CN) | FC, WB | Mouse IgG |
HPAB-0133CQ | Human Anti-GP6 Recombinant Antibody (clone hGP 5C4) | ELISA, FC, Inhib, FuncS | Humanized lgG1 |
HPAB-1711-FY | Human Anti-GP6 Recombinant Antibody (clone F1245-4-1) | ELISA, WB, IHC | Chimeric (mouse/human) IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0002-CN-F(E) | Human Anti-GP6 Recombinant Antibody; Fab Fragment (HPAB-0002-CN-F(E)) | FC, WB | Humanized Fab |
HPAB-0003-CN-F(E) | Human Anti-GP6 Recombinant Antibody; Fab Fragment (HPAB-0003-CN-F(E)) | FC, WB | Humanized Fab |
HPAB-0004-CN-F(E) | Mouse Anti-GP6 Recombinant Antibody; Fab Fragment (HPAB-0004-CN-F(E)) | FC, WB | Mouse Fab |
FAMAB-0288JF-F(E) | Human Anti-GP6 Recombinant Antibody (clone 10B12); Fab Fragment | FC, ELISA, FuncS | Human Fab |
FAMAB-0289JF-F(E) | Human Anti-GP6 Recombinant Antibody (clone 1C3); Fab Fragment | FC, ELISA, FuncS | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1711-FY-F(E) | Mouse Anti-GP6 Recombinant Antibody (clone F1245-4-1); scFv Fragment | ELISA, WB, IHC | Mouse scFv |
HPAB-1712-FY-F(E) | Mouse Anti-GP6 Recombinant Antibody (clone F1245-5-1); scFv Fragment | ELISA, WB, IHC | Mouse scFv |
HPAB-1713-FY-F(E) | Mouse Anti-GP6 Recombinant Antibody (clone F1245-6-2); scFv Fragment | ELISA, WB, IHC | Mouse scFv |
HPAB-1714-FY-F(E) | Human Anti-GP6 Recombinant Antibody (clone F1232-7-1); scFv Fragment | ELISA | Human scFv |
HPAB-1715-FY-F(E) | Human Anti-GP6 Recombinant Antibody (clone F1232-18-3); scFv Fragment | ELISA | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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