Human Anti-GP6 Recombinant Antibody (FAMAB-0289JF) (CAT#: FAMAB-0289JF)
Recombinant monoclonal antibody strongly binds to human the immunoglobulin-like ectodomains (residues 1-185) of glycoprotein VI, also called D1D2. This product is a human monoclonal antibody that can be useful in the treatment of damage to blood vessels.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HEL
(Immunofluorescent staining of human cell line HEL shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47611/1925_A11_24_cr5cd55a323d93f_selected.jpg
(Immunofluorescent staining of human cell line HEL shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47611/1925_A11_24_cr5cd55a323d93f_selected.jpg
Figure 2 IHC staining of human bone marrow
(Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in megakaryocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/66482/ihc_selected.jpg
(Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in megakaryocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/66482/ihc_selected.jpg
Figure 3 Cerebral cortex
(Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/66482/149862_B_9_5.jpg
(Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/66482/149862_B_9_5.jpg
Figure 4 Colon
(Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: nuclear Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/66482/149862_A_7_3.jpg
(Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: nuclear Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/66482/149862_A_7_3.jpg
Figure 5 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/66482/149862_A_8_5.jpg
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/66482/149862_A_8_5.jpg
Figure 6 Testis
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Sertoli cells Staining: Low Intensity: Weak Quantity: 75%-25% Spermatogonia cells Staining: Low Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/66482/149862_A_6_6.jpg
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Sertoli cells Staining: Low Intensity: Weak Quantity: 75%-25% Spermatogonia cells Staining: Low Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/66482/149862_A_6_6.jpg
Figure 7 RNA cell line category: Group enriched (HEL, K-562, U-2 OS)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000088053-GP6
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000088053-GP6
Specifications
- Host Species
- Human
- Derivation
- Human phage display scFv library
- Type
- Human IgG
- Specificity
- Human GP6
- Species Reactivity
- Human, mouse
- Applications
- FC, ELISA, FuncS
- Related Disease
- Damage to blood vessels
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Glycoprotein VI Platelet; Glycoprotein VI (Platelet); Glycoprotein 6; GPVI; Platelet Collagen Recept; Platelet Glycoprotein VI; BDPLT11; GPIV
- Gene ID
- 51206
- UniProt ID
- Q9HCN6
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "GP6"
Select a product category from the dropdown menu below to view related products.
Please select product type
Human Antibody Products
Mouse Antibody Products
Rabbit Monoclonal Antibody Products
ScFv Antibody Products
Fab Antibody Products
IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-003CT | Anti-Human GPVI Recombinant Antibody (1C3) | Funcs, ELISA, Inhib, FC | Human antibody |
| TAB-003CT-S(P) | Anti-Human GPVI Recombinant Antibody scFv Fragment (1C3) | Funcs, ELISA, Inhib, FC | Human antibody |
| TAB-003CT-F(E) | Anti-Human GPVI Recombinant Antibody Fab Fragment (1C3) | ELISA, Inhibition, FC | Human antibody |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for FAMAB-0289JF. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: WB, ELISA, FC, IP, FuncS, IF, Neut
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
Application: ELISA, FC, IP, FuncS, IF, Neut, WB
Application: ELISA, Neut, FuncS
Application: IHC, ELISA, FC, WB, ADCC, FuncS
Application: ELISA, WB, Neut, Funcs, IHC, Inhib
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, WB, Microarray, Block
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
