Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 3H6) (CAT#: MRO-4196CQ)

This product is a recombinant mouse anti-HIV-1 monoclonal antibody. 3H6 specifically binds to gp41.


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WB

Figure 1 Design and purification of Ab2/3H6Fab variants.

Figure 1 Design and purification of Ab2/3H6Fab variants.

Three different Ab2/3H6Fab preparations were developed for the immunization
study.

Mader, A., & Kunert, R. (2012). Evaluation of the potency of the anti-idiotypic antibody Ab2/3H6 mimicking gp41 as an HIV-1 vaccine in a rabbit prime/boost study. PloS one, 7(6).

ELISA

Figure 2 Binding of different immunized rabbit IgG fractions to Ab2/3H6Fab and UG37.

Figure 2 Binding of different immunized rabbit IgG fractions to Ab2/3H6Fab and UG37.

Purified rabbit IgG fractions immunized with
different Fab preparations, the pre-immune IgG fractions and the IgG fractions of the control animals were tested in a binding ELISA.

Mader, A., & Kunert, R. (2012). Evaluation of the potency of the anti-idiotypic antibody Ab2/3H6 mimicking gp41 as an HIV-1 vaccine in a rabbit prime/boost study. PloS one, 7(6).


Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Recognizes HIV-1 gp41
  • Species Reactivity
  • HIV-1
  • Clone
  • 3H6
  • Applications
  • ELISA, WB

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The HIV-1 gp41 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Western blot.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP41; gp41; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 3H6"

See other products for "HIV-1 gp41"

MHC Tetramer for Virology

CAT Product Name Application Type
MHC-LC746 A*2402/HIV-1 gp41 (RYLKDQQLL) MHC Tetramer FCM

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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