Recombinant mouse antibody to gp41. This Ab recognized trimeric ΔV2gp140 but not monomeric ΔV2gp140, suggesting that the epitope is affected by the state of Env oligomerization. P4A3 did not neutralize homologous SF162, nor viruses lacking V1 or V2 loops.
Figure 1 The binding of the anti-gp41 P4A3.
Data are the average of two independent experiments.
Derby, N. R., Gray, S., Wayner, E., Campogan, D., Vlahogiannis, G., Kraft, Z., ... & Stamatatos, L. (2007). Isolation and characterization of monoclonal antibodies elicited by trimeric HIV-1 Env gp140 protein immunogens. Virology, 366(2), 433-445.
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CAT | Product Name | Application | Type |
---|---|---|---|
MHH-486-F(E) | Recombinant Human Anti-HIV-1 gp41 Antibody Fab Fragment | ELISA, IP, FuncS | Fab |
PFBL-187 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 3BC176); Fab Fragment | Neut, FuncS | Human Fab |
PFBL-188 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 3BC315); Fab Fragment | Neut, FuncS | Human Fab |
PFBL-189 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone m66); Fab Fragment | Neut, FuncS | Human Fab |
PFBL-190 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 13H11); Fab Fragment | WB, ELISA, FuncS | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PABL-185 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 8062) | WB, ELISA, FuncS | Human IgG |
PABL-186 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 2F5) | WB, Neut, FuncS | Human IgG |
PABL-187 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 3BC176) | Neut, FuncS | Human IgG |
PABL-188 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 3BC315) | Neut, FuncS | Human IgG |
PABL-189 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone m66) | Neut, FuncS | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-025LC | Anti-HIV-1 gp41 Recombinant Antibody (4E10-IgG3) | ELISA | Human antibody |
MRO-026LC | Anti-HIV-1 gp41 Recombinant Antibody (4E10-IgG1) | ELISA | Human antibody |
MRO-040LC | Anti-HIV-1 gp41 Recombinant Antibody (M66.6) | ELISA | Human antibody |
MRO-074LC | Anti-HIV-1 gp41 Recombinant Antibody (W) | ELISA | Human antibody |
MRO-077LC | Anti-HIV-1 gp41 Recombinant Antibody (3D6) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-LC746 | A*2402/HIV-1 gp41 (RYLKDQQLL) MHC Tetramer | FCM |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBC-331 | Mouse Anti-HIV-1 gp41 Recombinant Antibody; scFv Fragment (PSBC-331) | Neut | Mouse scFv |
PSBC-332 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 10E8v4-5R+100cF); scFv Fragment | Neut | Human scFv |
PSBC-334 | Mouse Anti-HIV-1 gp41 Recombinant Antibody; scFv Fragment (PSBC-334) | ELISA, Neut | Mouse scFv |
PABJ-0150-S(P) | Human Anti-HIV-1 gp41 Recombinant Antibody (clone N6 FR3-03); scFv Fragment | ELISA, Neut | Human scFv |
PABJ-0179-S(P) | Human Anti-HIV-1 gp41 Recombinant Antibody; scFv Fragment (PABJ-0179-S(P)) | ELISA, Neut, FuncS | Human scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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