Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone P4A3) (CAT#: MRO-4187CQ)

Recombinant mouse antibody to gp41. This Ab recognized trimeric ΔV2gp140 but not monomeric ΔV2gp140, suggesting that the epitope is affected by the state of Env oligomerization. P4A3 did not neutralize homologous SF162, nor viruses lacking V1 or V2 loops.


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  • Published Data
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FC

Figure 1 The binding of the anti-gp41 P4A3.

Figure 1 The binding of the anti-gp41 P4A3.

Data are the average of two independent experiments.

Derby, N. R., Gray, S., Wayner, E., Campogan, D., Vlahogiannis, G., Kraft, Z., ... & Stamatatos, L. (2007). Isolation and characterization of monoclonal antibodies elicited by trimeric HIV-1 Env gp140 protein immunogens. Virology, 366(2), 433-445.


Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG2a, κ
  • Specificity
  • Recognizes HIV-1 gp41
  • Species Reactivity
  • HIV-1
  • Clone
  • P4A3
  • Applications
  • FC

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The HIV-1 gp41 antibody has been reported in applications of Flow Cytometry.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP41; gp41; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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MHC Tetramer for Virology

CAT Product Name Application Type
MHC-LC746 A*2402/HIV-1 gp41 (RYLKDQQLL) MHC Tetramer FCM

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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