Afuco™ Anti-ITGA4 and ITGB7 ADCC Recombinant Antibody (Vedolizumab), ADCC Enhanced (CAT#: AFC-TAB-H75)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant Humanized (from mouse) antibody to Human ITGA4+ITGB7. Vedolizumab (trade name vedolizumab) is a monoclonal antibody for the treatment of ulcerative colitis and Crohn's disease.It binds to integrin α4β7 (LPAM-1, lymphocyte Peyer's patch adhesion molecule 1). Blocking the α4β7 integrin results in gut-selective anti-inflammatory activity. It is marketed under the trade name vedolizumab.
Specific Inquiry
Specifications
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Specificity
- ITGA4_ITGB7(integrin alpha4 (CD49d)_beta7, integrin alpha4_beta7, integrin α4β7, lymphocyte Peyer s patch adhesion molecule 1, LPAM-1) [Homo sapiens]
- Species Reactivity
- Human
- Clone
- Vedolizumab
- Applications
- FC, IP, ELISA, Neut, FuncS, IF
- Conjugate
- Unconjugated
- Trade name
- Vedolizumab
- Generic Name
- Vedolizumab
- Related Disease
- Ulcerative colitis (UC)
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Vedolizumab; vedolizumab; 943609-66-3; MLN0002; MLN02; LDP02; ITGA4; ITGB7; Integrin α4β7; CD49d/β7
Related Resources
Please refer to Vedolizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Vedolizumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "vedolizumab"
Anti-Human ITGA4+ITGB7 Recombinant Antibody (Vedolizumab)Recombinant Humanized (from mouse) antibody to Human ITGA4+ITGB7. Vedolizumab (trade name vedolizumab) is a monoclonal antibody for the treatment of ulcerative colitis and Crohn's disease.It binds to integrin α4β7 (LPAM-1, lymphocyte Peyer's patch adhesion molecule 1). Blocking the α4β7 integrin results in gut-selective anti-inflammatory activity. It is marketed under the trade name vedolizumab.
See other products for "ITGA4 and ITGB7"
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H02 | Anti-Human ITGA4+ITGB7 Recombinant Antibody (Abrilumab) | IP, IF, FuncS, FC, Neut, ELISA, WB | IgG2 - kappa |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H75 | Anti-Human ITGA4+ITGB7 Recombinant Antibody (Vedolizumab) | FC, IP, ELISA, Neut, FuncS, IF, WB | IgG1 - kappa |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-H02 | Afuco™ Anti-ITGA4 and ITGB7 ADCC Recombinant Antibody (Abrilumab), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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