Recombinant Human Anti-LPS Antibody (216-01) (CAT#: HPAB-J0169-YC)

Provided is a human monoclonal antibody specific for LPS of the P. aeruginosa serotype IATS 01. The binding of 216-01 to LPS isolated from P. aeruginosa strains was determined by ELISA.


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ELISA

Figure 1 relates to the recognition pattern of LPS isolated from P. aeruginosa strains by the monoclonal antibody 216-01. The binding of 216-01 was determined by ELISA.

Figure 1 relates to the recognition pattern of LPS isolated from P. aeruginosa strains by the monoclonal antibody 216-01. The binding of 216-01 was determined by ELISA.

FuncS

Figure 2 relates to the opsonophagocytotic activity of the monoclonal antibody 216-01 and two other known antibodies (MAb C1 and MAb C2) directed against P. aeruginosa serotype IATS 01.

Figure 2 relates to the opsonophagocytotic activity of the monoclonal antibody 216-01 and two other known antibodies (MAb C1 and MAb C2) directed against P. aeruginosa serotype IATS 01.

FuncS

Figure 3 relates to the pharmocodynamics of the monoclonal antibody 216-01 in mice.

Figure 3 relates to the pharmocodynamics of the monoclonal antibody 216-01 in mice.

The in vivo protective capacity of 216O1 was assessed in a murine burn wound sepsis model. Different doses of 21601 were administered i.v. to NMRI mice. Survival rates are shown up to 96 h after challenge.


Specifications

  • Immunogen
  • LPS of the P. aeruginosa serotype IATS 01
  • Host Species
  • Human
  • Type
  • Human IgM, κ
  • Specificity
  • P. aeruginosa
  • Species Reactivity
  • P. aeruginosa
  • Clone
  • 216-01
  • Applications
  • ELISA, FuncS

Product Property

  • Storage
  • Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles

Applications

  • Application Notes
  • This antibody has been reported for use in Enzyme-Linked Immunosorbent Assay, Functional Assay.

Target

  • Alternative Names
  • Lipopolysaccharides

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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Single-domain Antibody

CAT Product Name Application Type
NABL-060 Recombinant Anti-V. cholerae O1 LPS VHH Single Domain Antibody WB, ELISA, IP, FuncS Llama VHH

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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