Recombinant Human Anti-LPS Antibody (216-01) (CAT#: HPAB-J0169-YC)
Provided is a human monoclonal antibody specific for LPS of the P. aeruginosa serotype IATS 01. The binding of 216-01 to LPS isolated from P. aeruginosa strains was determined by ELISA.
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Custom Production
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ELISA
Figure 1 relates to the recognition pattern of LPS isolated from P. aeruginosa strains by the monoclonal antibody 216-01. The binding of 216-01 was determined by ELISA.
FuncS
Figure 2 relates to the opsonophagocytotic activity of the monoclonal antibody 216-01 and two other known antibodies (MAb C1 and MAb C2) directed against P. aeruginosa serotype IATS 01.
FuncS
Figure 3 relates to the pharmocodynamics of the monoclonal antibody 216-01 in mice.
The in vivo protective capacity of 216O1 was assessed in a murine burn wound sepsis model. Different doses of 21601 were administered i.v. to NMRI mice. Survival rates are shown up to 96 h after challenge.
Specifications
- Immunogen
- LPS of the P. aeruginosa serotype IATS 01
- Host Species
- Human
- Type
- Human IgM, κ
- Specificity
- P. aeruginosa
- Species Reactivity
- P. aeruginosa
- Clone
- 216-01
- Applications
- ELISA, FuncS
Product Property
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-Linked Immunosorbent Assay, Functional Assay.
Target
- Alternative Names
- Lipopolysaccharides
Related Resources
Rheumatoid Arthritis
Graft-versus-Host Disease
TLR Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-630-F(E) | Recombinant Anti-LPS Antibody Fab Fragment | IF, FACS, FuncS | Fab |
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| PFBL-078 | Recombinant Mouse Anti-E. coli LPS Antibody Fab Fragment (WN1 222-5) | WB, ELISA, FuncS | Fab |
| PFBW-013 | Mouse Anti-LPS Recombinant Antibody (clone S45-18); Fab Fragment | WB, ELISA | Mouse Fab |
| FAMAB-0207-YC-F(E) | Recombinant Human Anti-LPS Antibody Fab Fragment (sc12) | ELISA, IF, WB | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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