H-2Db/Human VEGFR2/KDR fragment 1 (FSNSTNDILI) MHC Pentamer (CAT#: MHC-YF772)
MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed VEGFR2/KDR fragment 1-derived peptide of FSNSTNDILI sequence covering 614-624 and H-2Db molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HEL
(Immunofluorescent staining of human cell line HEL shows localization to nuclear membrane & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/73577/1825_D8_31_cr5ac340707076b_selected.jpg
(Immunofluorescent staining of human cell line HEL shows localization to nuclear membrane & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/73577/1825_D8_31_cr5ac340707076b_selected.jpg
Figure 2 Placenta
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4028/11467_A_2_7_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4028/11467_A_2_7_val_selected.jpg
Figure 3 Colon
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4028/11467_A_8_3.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4028/11467_A_8_3.jpg
Figure 4 Kidney
(Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4028/11467_A_7_5.jpg
(Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4028/11467_A_7_5.jpg
Figure 5 Testis
(Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4028/11467_A_6_6.jpg
(Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4028/11467_A_6_6.jpg
Figure 6 RNA cell line category: Group enriched (HUVEC TERT2, TIME)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000128052-KDR
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000128052-KDR
Specifications
- Allele
- H-2Db
- Class
- Class I
- Antigen
- VEGFR2/KDR fragment 1
- Antigen Species
- Human
- Peptide
- FSNSTNDILI
- Range
- 614-624
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
- Alternative Names
- Kinase Insert Domain Receptor; Kinase Insert Domain Receptor (A Type III Receptor Tyrosine Kinase); Vascular Endothelial Growth Factor Receptor 2; Protein-Tyrosine Kinase Receptor Flk-1; Fetal Liver Kinase 1; EC 2.7.10.1; VEGFR2; FLK1; Tyrosine Kinase Growth Factor Receptor;
- Gene ID
- 3791
- UniProt ID
- P35968
Downloads
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Humanized Antibody
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| TAB-202 | Humanized Anti-KDR Recombinant Antibody (clone Alacizumab); di - Fab' Fragment | IF, IP, Neut, FuncS, ELISA, FC, ICC | Humanized (from mouse) di - Fab' |
| TAB-411CQ | Anti-Human KDR Recombinant Antibody (HLX06) | ELISA | Humanized antibody |
| TAB-411CQ-S(P) | Anti-Human KDR Recombinant Antibody scFv Fragment (HLX06) | ELISA | Humanized antibody |
| TAB-411CQ-F(E) | Anti-Human KDR Recombinant Antibody Fab Fragment (HLX06) | ELISA | Humanized antibody |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-079 | Anti-Human VEGF Receptor 2 Recombinant Antibody (Ramucirumab) | FC, IHC | IgG1 - kappa |
| TAB-0298CL | Human Anti-KDR Recombinant Antibody (TAB-0298CL) | WB, FC, ELISA, Inhib, Neut, FuncS | Human IgG |
| TAB-0299CL | Human Anti-KDR Recombinant Antibody (TAB-0299CL) | WB, FC, Inhib, Neut | Human IgG |
| TAB-322CQ | Anti-Human KDR Recombinant Antibody (AK404R) | ELISA, WB, Inhib | Human antibody |
| TAB-325CQ | Human Anti-KDR Recombinant Antibody (TAB-325CQ) | ELISA, FC | Human IgG1, κ |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G047E | Anti-KDR immunotoxin (IgG1)-PE | Cytotoxicity assay, Function study |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-326CQ-S(P) | Rat Anti-Kdr Recombinant Antibody; scFv Fragment (TAB-326CQ-S(P)) | ELISA, FC, WB | Rat scFv |
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| TAB-332CQ-S(P) | Anti-Human KDR Recombinant Antibody scFv Fragment (4.13) | ELISA, FC, IHC | |
| TAB-326CQ-F(E) | Rat Anti-Kdr Recombinant Antibody; Fab Fragment (TAB-326CQ-F(E)) | ELISA, FC, WB | Rat Fab |
| TAB-331CQ-F(E) | Anti-Human KDR Recombinant Antibody Fab Fragment (6.64) | ELISA, FC, IHC |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0624MZ | Chicken Anti-VEGFR-2 Polyclonal IgY | IHC, WB | Chicken antibody |
| BRD-0709MZ | Chicken Anti-KDR Polyclonal IgY | WB | Chicken antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1619CQ | Recombinant Mouse Anti-KDR Antibody (23B31) | WB, IP, FC, Neut | |
| NEUT-1620CQ | Recombinant Rat Anti-Kdr Antibody (CBL840) | ELISA(Cap), Neut | IgG2a |
| NEUT-1621CQ | Recombinant Rat Anti-Kdr Antibody (CBL880) | Neut, WB | IgG2 |
| NEUT-1622CQ | Recombinant Mouse Anti-KDR Antibody (6B11) | WB, Neut | IgG1 |
| NEUT-1623CQ | Recombinant Mouse Anti-KDR Antibody (CBL505) | FC, CyTOF, Neut | IgG1 |
Rabbit Monoclonal Antibody
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| MOR-1927 | Hi-Affi™ Recombinant Rabbit Anti-KDR Monoclonal Antibody (DS1927AB) | IHC-P | IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0097-YC-F(E) | Rabbit Anti-KDR Recombinant Antibody; Fab Fragment (HPAB-0097-YC-F(E)) | ELISA, FuncS | Rabbit Fab |
| HPAB-0098-YC-F(E) | Rabbit Anti-KDR Recombinant Antibody; Fab Fragment (HPAB-0098-YC-F(E)) | ELISA, FuncS | Rabbit Fab |
| HPAB-0099-YC-F(E) | Rabbit Anti-KDR Recombinant Antibody; Fab Fragment (HPAB-0099-YC-F(E)) | ELISA, FuncS | Rabbit Fab |
| HPAB-0246-WJ-F(E) | Human Anti-KDR Recombinant Antibody; Fab Fragment (HPAB-0246-WJ-F(E)) | ELISA, IF, FC | Human Fab |
| HPAB-0567-WJ-F(E) | Human Anti-KDR Recombinant Antibody; Fab Fragment (HPAB-0567-WJ-F(E)) | ELISA, FC, WB | Human Fab |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-032CQ | Mouse Anti-KDR Antibody | WB, ELISA Capture | Mouse IgG1 |
| MOB-033CQ | Goat Anti-KDR Polyclonal Antibody | WB, ELISA(Det) | Goat IgG |
| MRO-2270-CN | Rabbit Anti-KDR Polyclonal Antibody (MRO-2270-CN) | IF, IHC, WB, FC | Rabbit IgG |
| HPAB-0141-WJ | Human Anti-KDR Recombinant Antibody (clone 2G1C12) | ELISA | Human IgG1, κ |
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ADCC Enhanced Antibody
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| AFC-TAB-079 | Afuco™ Anti-KDR ADCC Recombinant Antibody (Ramucirumab), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
scFv Fragment Antibody
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| HPAB-N0154-YC-S(P) | Mouse Anti-KDR Recombinant Antibody; scFv Fragment (HPAB-N0154-YC-S(P)) | ELISA, Inhib | Mouse scFv |
| HPAB-0016-YJ-S(P) | Mouse Anti-KDR Recombinant Antibody; scFv Fragment (HPAB-0016-YJ-S(P)) | RIA, ELISA | Mouse scFv |
| HPAB-1018WJ-S(P) | Rabbit Anti-KDR Recombinant Antibody (clone Mab29); scFv Fragment | ELISA, FC | Rabbit scFv |
| HPAB-1019WJ-S(P) | Rabbit Anti-KDR Recombinant Antibody (clone Mab27); scFv Fragment | ELISA, FC | Rabbit scFv |
| HPAB-1020WJ-S(P) | Rabbit Anti-KDR Recombinant Antibody (clone Mab20); scFv Fragment | ELISA, FC | Rabbit scFv |
Single-domain Antibody
| CAT | Product Name | Application | Type |
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| HPAB-0298-YJ-VHH | Recombinant Human Anti-KDR Nano Antibody (HPAB-0298-YJ-VHH) | Inhib | Human VHH |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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