H-2Db/Human VEGFR2/KDR fragment 1 (FSNSTNDILI) MHC Pentamer
CAT#: MHC-YF772
MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed VEGFR2/KDR fragment 1-derived peptide of FSNSTNDILI sequence covering 614-624 and H-2Db molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEL
Immunofluorescent staining of human cell line HEL shows localization to nuclear membrane & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/73577/1825_D8_31_cr5ac340707076b_selected.jpg
Normal Tissue
Figure 2 Placenta
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4028/11467_A_2_7_val_selected.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4028/11467_A_8_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4028/11467_A_7_5.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4028/11467_A_6_6.jpg
RNA Expression
Figure 6 RNA cell line category: Group enriched (HUVEC TERT2, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000128052-KDR
❮
❯
Specifications
- Allele
- H-2Db
- Class
- Class I
- MHC Species
- Mouse
- Antigen
- VEGFR2/KDR fragment 1
- Antigen Species
- Human
- Peptide
- FSNSTNDILI
- Range
- 614-624
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
- Alternative Names
- Kinase Insert Domain Receptor; Kinase Insert Domain Receptor (A Type III Receptor Tyrosine Kinase); Vascular Endothelial Growth Factor Receptor 2; Protein-Tyrosine Kinase Receptor Flk-1; Fetal Liver Kinase 1; EC 2.7.10.1; VEGFR2; FLK1; Tyrosine Kinase Growth Factor Receptor;
- Gene ID
- 3791
- UniProt ID
- P35968
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Datasheet
MSDS
COA
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