H-2Db/Human VEGFR2/KDR fragment 1 (FSNSTNDILI) MHC Pentamer (CAT#: MHC-YF772)

• Allele
• H-2Db

• Class
• Class I

• MHC Species
• Mouse

• Antigen
• VEGFR2/KDR fragment 1

• Antigen Species
• Human

• Peptide
• FSNSTNDILI

• Range
• 614-624

• Conjugate
• Unlabeled, Biotin, R-PE, APC

• Application
• FCM

• Antigen Introduction
• Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]

• Alternative Names
• Kinase Insert Domain Receptor; Kinase Insert Domain Receptor (A Type III Receptor Tyrosine Kinase); Vascular Endothelial Growth Factor Receptor 2; Protein-Tyrosine Kinase Receptor Flk-1; Fetal Liver Kinase 1; EC 2.7.10.1; VEGFR2; FLK1; Tyrosine Kinase Growth Factor Receptor;

• Gene ID
• 3791

• UniProt ID
• P35968

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