Human Anti-BoNT/B1 and B2 scFv-Fc Chimera (VS-0325-FY130) (CAT#: VS-0325-FY130)
The Anti-BoNT/B scFv-Fc antibodies are a pair of human-like fusion proteins designed for potential therapeutic use against botulism, a life-threatening disease caused by botulinum neurotoxins (BoNTs) produced by C. botulinum. Potential for use as an antitoxin in the treatment of botulism caused by BoNT/B2 subtypes.
Specific Inquiry
Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- C. botulinum BoNT/B1 and B2
- Species Reactivity
- C. botulinum
- Applications
- Neutralization
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- BoNT/B1, BoNT/B2
- Long Name
- Clostridium botulinum Botulinum Neurotoxin serotype B1 and B2
- Function
- Clostridium botulinum BoNT/B1 and B2 are botulinum neurotoxins that cause botulism by blocking neurotransmitter release at neuromuscular junctions. They are among the most potent toxins known and are used in therapeutic and cosmetic applications.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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