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    Human Anti-PTGFRN scFv-Fc Chimera (VS-0325-FY40) (CAT#: VS-0325-FY40)

    The anti-PTGFRN scFv-Fc antibody targets Prostaglandin F Receptor Null (PTGFRN), a protein involved in prostaglandin signaling pathways. It is designed to modulate PTGFRN function, which may have therapeutic implications in inflammatory and cardiovascular diseases.

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    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IHC staining of human cervix, uterine
    Figure 1 IHC staining of human cervix, uterine
    (Immunohistochemical staining of human cervix, uterine shows membranous positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/17074/38410_B_7_3_selected.jpg
    Normal Tissue
    Figure 2 Cerebral cortex
    Figure 2 Cerebral cortex
    (Neuronal cells
    Staining: Low
    Intensity: Moderate
    Quantity: <25%
    Location: Cytoplasmic/membranous
    Neuropil
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/17074/38410_B_7_5.jpg
    Figure 3 Colon
    Figure 3 Colon
    (Endothelial cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Glandular cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/17074/38410_A_9_3.jpg
    Figure 4 Liver
    Figure 4 Liver
    (Cholangiocytes
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Hepatocytes
    Staining: Low
    Intensity: Moderate
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/17074/38410_A_7_4.jpg
    Figure 5 Kidney
    Figure 5 Kidney
    (Cells in tubules
    Staining: Low
    Intensity: Moderate
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/17074/38410_A_8_5.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Leydig cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/17074/38410_A_5_6.jpg
    RNA Expression
    Figure 7 RNA cell line category: Cell line enhanced (U-87 MG, WM-115)
    Figure 7 RNA cell line category: Cell line enhanced (U-87 MG, WM-115)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000134247-PTGFRN/subcellular

    Specifications

    • Immunogen
    • Human PTGFRN-ECD (extracellular domain; amino-acid 26-832).
    • Host Species
    • Human
    • Type
    • Human IgG1, scFv-Fc
    • Specificity
    • Human PTGFRN
    • Species Reactivity
    • Human
    • Applications
    • ADC, Immunofluorescence
    • Related Disease
    • Cardiovascular disease

    Product Property

    • Purity
    • >95% as determined by SDS-PAGE
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
    • Shipping
    • Ice packs

    Target

    • Alternative Names
    • FPRP; CD315; EWI-F; CD9P-1; SMAP-6
    • Long Name
    • Prostaglandin F2 Receptor Inhibitor
    • Cellular Localization
    • Endoplasmic reticulum membrane; Golgi apparatus, trans-Golgi network membrane
    • Post Translation Modifications
    • Glycosylation at Asn44, Ser150, Asn286, Asn300, Asn383, Asn413, Asn525, Asn600, Asn618, and Asn691
      Modification sites at PhosphoSitePlus
      Glycosylation from GlyConnect FPRP_HUMAN (1647)
      Glycosylation from GlyGen
    • Function
    • PTGFRN (Prostaglandin F receptor negative regulator) plays a role in regulating prostaglandin signaling. It is involved in controlling the activity of the prostaglandin F receptor, and therefore influences processes mediated by prostaglandins. It has impacts on things like cell growth and inflammation.

    Recommended Products

    Isotype Control

    Secondary Antibody

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "PTGFRN"

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    IgG Antibody Products
    CAT Product Name Application Type
    MOB-3429z Mouse Anti-PTGFRN Recombinant Antibody (clone 40H1) WB, ELISA, FC, FuncS Mouse IgG1

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