Mouse Anti-MARV GP (clone CAN30G5) scFv-Fc Chimera
CAT#: VS-0125-FY99
The anti-MARV GP scFv-Fc protein is a recombinant antibody specifically targeting the glycoprotein of the Marburg virus (MARV), which has attracted widespread attention in the field of viral infection therapy in recent years. Studies have shown that this protein exhibits good neutralizing activity against the Marburg virus under laboratory conditions and demonstrates significant protective effects in animal models. This finding lays a solid foundation for the future development of therapies against the Marburg virus and provides important research ideas for the treatment of other similar viruses. By further optimizing and improving the properties of this antibody, it is expected that its efficacy and safety in clinical applications can be enhanced. Moreover, the results of this research not only help address the public health threat posed by the Marburg virus but also indicate a direction for the development of antiviral biopharmaceuticals.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG2, scFv-Fc
- Species Reactivity
- Marburg virus (MARV)
- Clone
- CAN30G5
- Applications
- Neutralization
- Related Disease
- Marburg virus (MARV) infection
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Stabilizer
- No Stabilizers
- Sterility
- 0.2 μM filtered
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- These antibody fragments (scFv-Fc) demonstrated 75%-100% protective efficacy in mouse experiments, indicating their ability to effectively neutralize Marburg virus infection. This suggests that they have the potential to serve as candidate therapeutics for MARV infection.
Target
- Alternative Names
- Marburg virus glycoprotein, GP (Glycoprotein), GP1,2 (referring to the glycoprotein's subunits), MBG, Marburg virus glycoprotein gene
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
See other products for "MARV GP"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0335MC | Rabbit Anti-MARV GP Antibody | WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0806CQ | Recombinant Mouse Anti-MARV GP Antibody (7G8) | WB, ELISA | IgG |
| EPAF-0807CQ | Recombinant Mouse Anti-MARV GP Antibody (3H5) | WB, Inhib | IgG |
| EPAF-0808CQ | Recombinant Mouse Anti-MARV GP Antibody (7E10) | WB, IP | IgG |
| EPAF-0809CQ | Recombinant Mouse Anti-MARV GP Antibody (7E9) | WB, IP | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0618WJ | Human Anti-MARV GP Recombinant Antibody (FAMAB-0618WJ) | ELISA, WB, Neut | Human IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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