Mouse Anti-TIE1 scFv-Fc Chimera (VS-0325-FY15)
CAT#: VS-0325-FY15
The anti-TIE1 scFv-Fc antibody targets TIE1, a receptor involved in maintaining vascular integrity and endothelial cell function. It can modulate TIE1 signaling, potentially affecting vascular stability and permeability. The scFv-Fc format provides high specificity and prolonged half-life, enhancing its utility in research and therapeutic applications.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Group enriched (EFO-21, HUVEC TERT2, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000066056-TIE1
❮
❯
Specifications
- Immunogen
- The purified human Tie-2-Fc protein.
- Host Species
- Mouse
- Type
- Mouse IgG1, scFv-Fc
- Specificity
- Human TIE1
- Species Reactivity
- Human
- Applications
- ELISA, Flow Cytometry
- Related Disease
- Vascular-related disease
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Tyrosine Kinase With Immunoglobulin Like And EGF Like Domains 1; Tyrosine Kinase With Immunoglobulin And Epidermal Growth Factor Homology Domains 1; EC 2.7.10.1; TIE; Tyrosine Kinase With Immunoglobulin-Like And EGF-Like Domains 1; Tyrosine-Protein Kinase Receptor Tie-1; EC 2.7.10; JTK14
- Gene ID
- 7075
- UniProt ID
- P35590
- Long Name
- Tyrosine Kinase With Immunoglobulin Like And EGF Like Domains 1
- Sequence Similarities
- Belongs to the protein kinase superfamily.
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Phosphorylated on tyrosine residues in response to ANGPT1, most likely by TEK/TIE2.
Glycosylation at Asn83, Asn161, Asn503, Asn596, and Asn709
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 6 sites, 3 N-linked glycans (1 site), 1 O-linked glycan (1 site)
- Protein Refseq
- XP_005271220.1; XP_016857696.1; XP_047285299.1; XP_047285310.1; XP_054194526.1
- Function
- Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis.
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0325-FY15. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
See other products for "TIE1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-608CL | Human Anti-TIE1 Recombinant Antibody (TAB-608CL) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0314CQ | Human Anti-TIE1 Recombinant Antibody (HPAB-0314CQ) | ELISA, FC, WB, IHC, IF, Inhib, Agonist | Human IgG1, κ |
| HPAB-0315CQ | Human Anti-TIE1 Recombinant Antibody (HPAB-0315CQ) | ELISA, FC, WB, IHC, IF, Block | Human IgG1, κ |
| HPAB-0316CQ | Human Anti-TIE1 Recombinant Antibody (HPAB-0316CQ) | ELISA, FC, WB, IHC, IF, Block | Human IgG1, κ |
| MRO-2223-CN | Rabbit Anti-TIE1 Polyclonal Antibody (MRO-2223-CN) | WB, IF, IHC | Rabbit IgG |
| VS3-WK1255 | Mouse Anti-TIE1 Recombinant Antibody (VS3-WK1255) | ELISA, WB | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0314CQ-F(E) | Human Anti-TIE1 Recombinant Antibody; Fab Fragment (HPAB-0314CQ-F(E)) | ELISA, FC, WB, IHC, IF, Agonist | Human Fab |
| HPAB-0315CQ-F(E) | Human Anti-TIE1 Recombinant Antibody; Fab Fragment (HPAB-0315CQ-F(E)) | ELISA, FC, WB, IHC, IF, Block | Human Fab |
| HPAB-0316CQ-F(E) | Human Anti-TIE1 Recombinant Antibody; Fab Fragment (HPAB-0316CQ-F(E)) | ELISA, FC, WB, IHC, IF, Block | Human Fab |
| HPAB-0317CQ-F(E) | Human Anti-TIE1 Recombinant Antibody; Fab Fragment (HPAB-0317CQ-F(E)) | ELISA, FC, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0314CQ-S(P) | Human Anti-TIE1 Recombinant Antibody; scFv Fragment (HPAB-0314CQ-S(P)) | ELISA, FC, WB, IHC, IF, Agonist | Human scFv |
| HPAB-0315CQ-S(P) | Human Anti-TIE1 Recombinant Antibody; scFv Fragment (HPAB-0315CQ-S(P)) | ELISA, FC, WB, IHC, IF, Block | Human scFv |
| HPAB-0316CQ-S(P) | Human Anti-TIE1 Recombinant Antibody; scFv Fragment (HPAB-0316CQ-S(P)) | ELISA, FC, WB, IHC, IF, Block | Human scFv |
| HPAB-0317CQ-S(P) | Human Anti-TIE1 Recombinant Antibody; scFv Fragment (HPAB-0317CQ-S(P)) | ELISA, FC, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC581 | Recombinant Anti-TIE1 Vesicular Antibody, EV Displayed (VS-0425-YC581) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7254 | Anti-TIE1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7255 | Anti-Human TIE1 Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: WB, IF, IP, Neut, FuncS, ELISA, FC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application:
-2-1.png)
Application: ELISA
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: WB, ELISA, FC, IHC, IF, IP
Application: ELISA, FuncS
Application: ELISA, Neut
-4.jpg)
Application: FC
Application: ELISA, Block, WB, FC, IP
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
