Mouse Anti-TIE1 scFv-Fc Chimera (VS-0325-FY15) (CAT#: VS-0325-FY15)

• Immunogen
• The purified human Tie-2-Fc protein.

• Host Species
• Mouse

• Type
• Mouse IgG1, scFv-Fc

• Specificity
• Human TIE1

• Species Reactivity
• Human

• Applications
• ELISA, Flow Cytometry

• Related Disease
• Vascular-related disease

• Purity
• >95% as determined by SDS-PAGE

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Shipping
• Ice packs

• Alternative Names
• Tyrosine Kinase With Immunoglobulin Like And EGF Like Domains 1; Tyrosine Kinase With Immunoglobulin And Epidermal Growth Factor Homology Domains 1; EC 2.7.10.1; TIE; Tyrosine Kinase With Immunoglobulin-Like And EGF-Like Domains 1; Tyrosine-Protein Kinase Receptor Tie-1; EC 2.7.10; JTK14

• Gene ID
• 7075

• UniProt ID
• P35590

• Long Name
• Tyrosine Kinase With Immunoglobulin Like And EGF Like Domains 1

• Sequence Similarities
• Belongs to the protein kinase superfamily.

• Cellular Localization
• Cell membrane

• Post Translation Modifications
• Phosphorylated on tyrosine residues in response to ANGPT1, most likely by TEK/TIE2.
  Glycosylation at Asn83, Asn161, Asn503, Asn596, and Asn709
  Modification sites at PhosphoSitePlus
  Glycosylation from GlyGen 6 sites, 3 N-linked glycans (1 site), 1 O-linked glycan (1 site)

• Protein Refseq
• XP_005271220.1; XP_016857696.1; XP_047285299.1; XP_047285310.1; XP_054194526.1

• Function
• Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis.

Secondary Antibody

• 2ND-029CQ
• Goat Anti-Human IgG Fc Antibody

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