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ADAM10
Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. ADAM10 encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. It cleaves the membrane-bound precursor of TNF-alpha at '76-Ala-|-Val-77' to its mature soluble form. It is responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. It is responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2, CD44, CDH2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP). It contributes to the normal cleavage of the cellular prion protein. It is involved in the cleavage of the adhesion molecule L1 at the cell surface and in released membrane vesicles, suggesting a vesicle-based protease activity.
Recombinant Mouse Anti-ADAM10 Antibody scFv Fragment (8C7) (HPAB-0101-YJ-S(P))
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- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: IP, Inhib, FuncS
Recombinant Mouse Anti-ADAM10 Antibody (8C7) (HPAB-0101-YJ)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG1, κ
- Application: IP, Inhib, FuncS
Recombinant Mouse Anti-ADAM10 Antibody Fab Fragment (8C7) (HPAB-0101-YJ-F(E))
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- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: IP, Inhib, FuncS
Recombinant Rabbit Anti-ADAM10 Polyclonal Antibody (CBPCN-009) (MRO-1627-CN)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC
Hi-Affi™ Recombinant Rabbit Anti-ADAM10 Monoclonal Antibody (DS68AB) (MOR-0068)
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IP
Recombinant Anti-Human ADAM10 Antibody scFv Fragment (MOB-2188z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: FC, Neut, Funcs
Recombinant Anti-Human ADAM10 Antibody Fab Fragment (MOB-2188z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: IF, Neut, FuncS
Recombinant Anti-Human ADAM10 Antibody (MOB-2188z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, Dot, FuncS
Recombinant Rabbit Anti-ADAM10 Monoclonal Antibody (JM32-11) (MRO-0029-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IP
Recombinant Mouse Anti-Human ADAM10 Antibody (clone 22H3) (MOB-0433MZ)
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- Species Reactivity: human
- Type: Mouse antibody
- Application: FC, IHC-P, IP, WB
Recombinant Anti-human ADAM10 Intrabody [Tat] (IAB-B003(T))
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- Species Reactivity: human
- Type: scFv-Tat
- Application: FACS, ICC, FuncS
Recombinant Anti-human ADAM10 Intrabody [+36 GFP] (IAB-B003(G))
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- Species Reactivity: human
- Type: scFv-(+36GFP)
- Application: FACS, ELISA, IF, FuncS
Recombinant Anti-human ADAM10 Intrabody [(D-Arg)9] (IAB-B003(A))
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- Species Reactivity: human
- Type: scFv-(D-Arg)9
- Application: PCA, WB, FuncS
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