Anti-ANXA2 Products

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For Research Use Only. Not For Clinical Use.

Creative Biolabs offers a range of highly specific anti-ANXA2 antibodies that are designed to assist researchers studying the role of ANXA2 in metastasis, angiogenesis, and fibrinolysis. Annexin A2 (ANXA2), a multifunctional protein, is a validated target in these processes, and our selection of high-quality recombinant antibodies will provide you with the sensitive and robust reagents you need to fully explore the biology of ANXA2, and to validate its potential as a therapeutic target.

ANXA2: A Multifunctional Protein in Angiogenesis and Metastasis

ANXA2 is a calcium- and phospholipid-binding protein that has been associated with a wide range of cellular processes. It has an essential role in organizing the cell membrane and in the regulation of ion channels and other membrane proteins. ANXA2 is also a plasminogen receptor, where it acts to promote fibrinolysis. Aberrant expression of ANXA2 is a feature of many aggressive cancers and it has been shown to play a role in tumor growth, invasion, and angiogenesis. For this reason, ANXA2 has become a widely studied biomarker and therapeutic target.

Alternative Names

ANXA2; Chromobindin 8; HEL-S-270; Annexin-2; Protein I; P36; Lipocortin II; ANX2L4; Epididymis Secretory Protein Li 270; ANX2; LPC2; Placental Anticoagulant Protein IV; Calpactin I Heavy Polypeptide; Annexin II

Background

This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-ANXA2 rAb Products

Our anti-ANXA2 recombinant antibodies are made for exceptional performance and reliability. Engineered with high-precision for high specificity and affinity, our recombinant antibodies can help you accurately detect ANXA2 in its different cellular locations: cytosolic, membrane-bound and extracellular. These carefully validated rAbs are designed to have minimal non-specific interactions, providing the clean and reproducible data that you need to help power your most complex research projects.

Table 1. Featured anti-ANXA2 recombinant antibody products at Creative Biolabs.

Creative Quality Control

At Creative Biolabs, quality assurance is a priority. Our anti-ANXA2 recombinant antibodies are produced via a robust, high-tech pipeline with quality checkpoints at every stage of production. We perform extensive validation, including specificity testing in ANXA2-knockout models where available, to ensure performance and lot-to-lot consistency. It's this level of commitment to quality and consistency that allows us to deliver antibodies you can count on to provide reproducible results in your most important experiments.

Customer Reviews

rAb Production

Creative Biolabs has access to a wide variety of expression systems that are used to make high-quality anti-ANXA2 recombinant antibodies. We have the capacity to engineer antibody fragments on prokaryotic platforms, and also have significant experience with eukaryotic systems like mammalian and yeast for full-length antibodies which need specific post-translational modifications. This flexible capacity allows us to deliver the most active and stable antibodies to meet the demands of your research.

Featured Anti-ANXA2 Recombinant Antibody Production Platforms
Fig.4 Milligram-scale anti-ANXA2 recombinant antibody production.

Fig.5 Gram-scale anti-ANXA2 recombinant antibody production.

rAb Modalities

Creative Biolabs has the capacity to produce a wide variety of customizable anti-ANXA2 recombinant antibody modalities to power innovation in your research. We can make standard IgGs for preclinical models, or can engineer specialty formats like Fabs for structural biology work and bispecific antibodies for therapeutic research and development. Our team can work with you to create custom solutions to the specific challenges in your research and R&D pipeline.

Fig.6 Full-length anti-ANXA2 recombinant antibody production and modalities.

ANXA2-Targeted Drug Information

Table 2. Public drug targeting ANXA2.

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

Drive your research forward with the superior quality of Creative Biolabs' anti-ANXA2 recombinant antibodies. Our portfolio delivers the high specificity, rigorous validation, and dependable consistency required to investigate this key protein in cancer and vascular biology. Trust in our expertise to provide reliable tools for your most important discoveries. Contact our scientific team today for more information.