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BDNF
Anti-BDNF Recombinant Antibody Products
- Mouse Anti-BDNF Recombinant Antibody (VS3-CJ800) (VS3-CJ800)
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- Species Reactivity: Mouse, Rat
- Type: Mouse IgG
- Application: WB
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- Species Reactivity: Human, Mouse, Rat, Zebrafish
- Type: Rabbit IgG
- Application: WB, ICC, IF, IHC
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- Rabbit Anti-BDNF Recombinant Antibody (clone CBACN-065) (MRO-0166-CN)
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- Species Reactivity: Human, Mouse, Rat, Zebrafish
- Type: Rabbit IgG
- Application: WB, IHC, IF
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- Rabbit Anti-BDNF Polyclonal Antibody (MRO-1686-CN) (MRO-1686-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC
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- Human Anti-BDNF Recombinant Antibody (clone R3BH1) (HPAB-0351-FY)
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- Derivation: Chimeric (chicken/human)
- Species Reactivity: Human
- Type: Chimeric (chicken/human) IgG1, λ
- Application: ELISA, Inhib, FuncS, Neut
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- Recombinant Anti-human BDNF Antibody (MOB-107)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, Dot, FuncS
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- Recombinant Human Anti-human BDNF Antibody Fab Fragment (MHH-107-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, WB, Neut, FuncS
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- Recombinant Human Anti-human BDNF Antibody scFv Fragment (MHH-107-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, IF, FuncS
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- Recombinant Anti-human BDNF Antibody Fab Fragment (MOB-107-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, IP, FuncS
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- Recombinant Anti-human BDNF Antibody scFv Fragment (MOB-107-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: FC, RIA, Biosensors, FuncS
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- Chicken Anti-BDNF Recombinant Antibody (clone R3BH1); scFv Fragment (HPAB-0351-FY-S(P))
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- Species Reactivity: Human
- Type: Chicken scFv
- Application: Block
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- Human Anti-BDNF Recombinant Antibody (clone R3BH1); Fab Fragment (HPAB-0351-FY-F(E))
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- Derivation: Chimeric (chicken/human)
- Species Reactivity: Human
- Type: Chimeric (chicken/human) Fab, λ
- Application: Block
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.
Protein class
Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, RAS pathway related proteins
Predicted location
Intracellular, Membrane, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Alveolar cells type 1, Smooth muscle cells, Excitatory neurons, Bipolar cells, Theca cells, Cardiomyocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (BJ, BJ hTERT+ SV40 Large T+, BJ hTERT+ SV40 Large T+ RasG12V, HBF TERT88, U-138 MG)
Interaction
Monomers and homodimers. Binds to NTRK2/TRKB (PubMed:8527932, 11152678). Can form heterodimers with other neurotrophin family members, such as NTF3 and NTF4 (in vitro), but the physiological relevance of this is not clear (PubMed:7703225, 10631974). BDNF precursor form: interacts with the heterodimer formed by NGFR and SORCS2 (PubMed:24908487).
Molecular function
Growth factor
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