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CD37 & saporin
Engineered Antibody Products
Hexamer Antibody Products
AbPlus
Recombinant Antibody Products
Functional Antibody Products
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Anti-CD37 & saporin Recombinant Antibody Products
- Anti-CD37 (K7153A)-SMCC-DM1 ADC (IMGN529) (ADC-L019)
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- Target: CD37
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto- 1-oxopropyl)maytansine)
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- Target: CD37
- Linker: mc-val-cit-PABC (cleavable maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
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- Anti-CD37-vc-MMAE ADC (ADC-037LZY)
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- Target: CD37
- Linker: VC (Valine-citrulline)
- Drug: MMAE (monomethyl auristatin E)
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- Anti-CD37-SMCC-maytansinoid ADC (ADC-016LZY)
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- Target: CD37
- Linker: SMCC(Maleimidomethyl cyclohexane-1-carboxylate)
- Drug: maytansinoid
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- Anti-CD37 (K7153A)-SMCC-DM1 ADC (ADC-064LCT)
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- Target: CD37
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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For Research Use Only. Not For Clinical Use.
Saporin is a so-called ribosome inactivating protein (RIP), due to its N-glycosidase activity, from the seeds of Saponaria officinalis (common name: soapwort).Saporin depurinate the ribosomal RNA in a specific position; rendering the large subunit of ribosomes unable to bind the elongation factors. The consequent arrest of protein synthesis is responsible for the cytotoxicity.
CD37 (CD37 Molecule) is a Protein Coding gene. Among its related pathways are Hematopoietic cell lineage. An important paralog of this gene is CD82.
