GD3 ganglioside
Anti-GD3 ganglioside Recombinant Antibody Products
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- Species Reactivity: Human
- Type: Mouse IgG3, κ
- Application: ELISA, FC, Cyt
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1, κ
- Application: ELISA, FC, Cyt
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric (mouse/human) IgG
- Application: ELISA
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- Type: Mouse IgG
- Application: ELISA
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- Type: Mouse IgG
- Application: IHC, TLC immunostaining
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- Species Reactivity: Human
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- Species Reactivity: Human
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- Species Reactivity: Human
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- Species Reactivity: Human
- Type: Human IgM
- Application: ELISA
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric (mouse/human) Fab
- Application: ELISA
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- Type: Mouse Fab
- Application: ELISA
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- Type: Mouse scFv
- Application: ELISA
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- Type: Mouse scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC, Cyt
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC, Cyt
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC, Cyt
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC, Cyt
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For Research Use Only. Not For Clinical Use.
This is a chimeric monoclonal antibody being developed for the treatment of malignant melanoma.
GD3 ganglioside is abundantly expressed on all melanomas but not expressed on most normal tissues. Gangliosides are complex glycolipid constituents of cell membranes. They are involved in many biological functions including cell-cell recognition, cell-matrix attachment, cell growth and cell differentiation. They are synthesized in the Golgi apparatus of the cell as a consequence of multienzyme pathways leading to different substructures.