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NKX2-2
Anti-NKX2-2 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene contains a homeobox domain and may be involved in the morphogenesis of the central nervous system. This gene is found on chromosome 20 near NKX2-4, and these two genes appear to be duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear transcription factor.
Protein class
Transcription factors
Predicted location
Intracellular
Single cell type specificity
Group enriched (Enteroendocrine cells, Oligodendrocytes, Oligodendrocyte precursor cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (HAP1, T-47d, U-138 MG, U-2 OS, WM-115)
Interaction
Interacts with OLIG2.
Molecular function
Activator, Developmental protein, DNA-binding
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