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For Research Use Only. Not For Clinical Use.
Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins
Intracellular
Cell type enhanced (Extravillous trophoblasts, Endometrial stromal cells, Leydig cells, Syncytiotrophoblasts)
Not detected in immune cells
Group enriched (PC-3, SK-BR-3)
Homotetramer (Ref. 18, PubMed:24947669). Interacts (when phosphorylated at Ser-19) with YWHAG; one YWHAG dimer bounds to one TH tetramer, this interaction may influence the phosphorylation and dephosphorylation of other sites (PubMed:24947669).
Monooxygenase, Oxidoreductase