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TM4SF1

Anti-TM4SF1 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas.
Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Basal prostatic cells, Urothelial cells, Prostatic glandular cells, Pancreatic endocrine cells, Endothelial cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (CAPAN-2, hTERT-RPE1, HUVEC TERT2, LHCN-M2, OE19)

Interaction

Present in high molecular weight complexes in tumor cells. Interacts with SDCBP2 (PubMed:11102519).

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