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VAV2
Anti-VAV2 Recombinant Antibody Products
- Rabbit Anti-VAV2 Recombinant Antibody (clone CBACN-575) (MRO-1573-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, IP
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- Rabbit Anti-VAV2 Recombinant Antibody (VS3-CJ1031) (VS3-CJ1031)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, ICC, IHC, IP
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- Mouse Anti-VAV2 Recombinant Antibody (clone 3B11E4) (VS3-XY1582)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, FC
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- Mouse Anti-VAV2 Recombinant Antibody (clone 5D2C4) (VS3-XY1583)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, FC
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For Research Use Only. Not For Clinical Use.
VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Hepatocytes, Inhibitory neurons)
Immune cell specificity
Immune cell enhanced (memory B-cell)
Cell line specificity
Low cell line specificity
Interaction
Interacts (via SH2 domains) with the phosphorylated form of EPHA2. Interacts with SSX2IP (By similarity). Interacts with NEK3 and PRLR and this interaction is prolactin-dependent.
Molecular function
Guanine-nucleotide releasing factor
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Related Signaling Pathways
FcεR1 Signaling Pathway
TCR Signaling Pathway