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    Anti-Human CD4 Recombinant Antibody (TRX1) (CAT#: TAB-168LC)

    The antibody reduces the density of CD4 expressed on T-cell surfaces that can engage in an immune response, thereby decreasing the count of functional CD4⁺ effector T lymphocytes. Additionally, the antibody, cat# TAB-168LC, hampers the activity of natural killer (NK) cells in laboratory settings.

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    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    We require custom production
    • Published Data
    • Gene Expression
    • Datasheet
    • MSDS
    • COA

    Figure 1 Comparison of model-predicted and digitized clearance for TRX1, MTRX1011a, rituximab, and daclizumab.

    Figure 1 Comparison of model-predicted and digitized clearance for TRX1, MTRX1011a, rituximab, and daclizumab.

    Non-compartmental analysis was performed to determine the mean and standard deviation of model-predicted clearance for each mAb (gray bars) and compare with observed clearances for each mAb (black bars).

    Glassman, P. M., & Balthasar, J. P. (2017, February). Physiologically-based modeling to predict the clinical behavior of monoclonal antibodies directed against lymphocyte antigens. In MAbs (Vol. 9, No. 2, pp. 297-306). Taylor & Francis.


    Specifications

    • Host Species
    • Human
    • Derivation
    • Humanized
    • Type
    • Humanized antibody
    • Specificity
    • Human
    • Clone
    • TRX1
    • Applications
    • ELISA
    • Related Disease
    • Autoimmune diseases

    Target

    • Alternative Names
    • CD4mut; CD4

    Related Resources

    • Related Diseases

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

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    CAT Product Name Application Type
    TAB-039 Anti-Human CD4 Recombinant Antibody (Zanolimumab) Neut, ELISA, IF, IP, FuncS, FC, IHC IgG1 - kappa

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    For Research Use Only. Not For Clinical Use.

    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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