Anti-Human CD4 Recombinant Antibody (TRX1) (CAT#: TAB-168LC)
The antibody reduces the density of CD4 expressed on T-cell surfaces that can engage in an immune response, thereby decreasing the count of functional CD4⁺ effector T lymphocytes. Additionally, the antibody, cat# TAB-168LC, hampers the activity of natural killer (NK) cells in laboratory settings.
Specific Inquiry
Figure 1 Comparison of model-predicted and digitized clearance for TRX1, MTRX1011a, rituximab, and daclizumab.
Non-compartmental analysis was performed to determine the mean and standard deviation of model-predicted clearance for each mAb (gray bars) and compare with observed clearances for each mAb (black bars).
Glassman, P. M., & Balthasar, J. P. (2017, February). Physiologically-based modeling to predict the clinical behavior of monoclonal antibodies directed against lymphocyte antigens. In MAbs (Vol. 9, No. 2, pp. 297-306). Taylor & Francis.
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized antibody
- Specificity
- Human
- Clone
- TRX1
- Applications
- ELISA
- Related Disease
- Autoimmune diseases
Target
Related Resources
Primary Immunodeficiency
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-039 | Anti-Human CD4 Recombinant Antibody (Zanolimumab) | Neut, ELISA, IF, IP, FuncS, FC, IHC | IgG1 - kappa |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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