This immunotoxin was achieved by conjugating/fusing the Anti-CD4 monoclonal antibody to Pseudomonas exotoxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to tumor cells. Once bind, the toxin enters cells by receptor-mediated endocytosis. Then PE cleaved fragments the size of Mr 37000 and 27000, the large fragment and finally into the Golgi and elongation factor 2 (EM) combining it glycosylation inactivation, inhibition of protein synthesis, leading to apoptosis. It was designed for treating acute lymphoblastic leukemias (ALL).
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1067z | Mouse Anti-CD4 Recombinant Antibody (clone 34D6) | FC, FuncS, ICC, IF, IP, WB | Mouse IgG2b, κ |
MOB-0272MZ | Mouse Anti-CD4 Recombinant Antibody (clone 5C13) | IHC | Mouse IgG1 |
FAMAB-0048CQ | Mouse Anti-CD4 Recombinant Antibody (clone Leu3a) | ELISA, FC, Block, FuncS | Mouse IgG1, κ |
MRO-1750-CN | Rabbit Anti-CD4 Polyclonal Antibody (MRO-1750-CN) | WB, IF, IHC, FC | Rabbit IgG |
MRO-1751-CN | Rabbit Anti-CD4 Polyclonal Antibody (MRO-1751-CN) | WB, IF, IHC, FC | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-039 | Anti-Human CD4 Recombinant Antibody (Zanolimumab) | Neut, ELISA, IF, IP, FuncS, FC, IHC | IgG1 - kappa |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-164 | Anti-Human CD4 Recombinant Antibody (Priliximab) | WB, FuncS, IF, Neut, ELISA, FC, IP | IgG1 - kappa |
TAB-167LC | Anti-Human CD4 Recombinant Antibody (cM-T412) | ELISA, Inhib | Chimeric antibody (mouse/human) |
TAB-170LC | Human Anti-CD4 Recombinant Antibody (TAB-170LC) | ELISA, FC, ADCC, CDC, SPR | Chimeric antibody (rat/human) |
TAB-162LC-S(P) | Anti-Human CD4 Recombinant Antibody scFv Fragment | ELISA | Chimeric antibody (mouse/human) |
TAB-164LC-S(P) | Monkey Anti-CD4 Recombinant Antibody; scFv Fragment (TAB-164LC-S(P)) | FC, SPR, ELISA | Monkey scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-G078R | Anti-CD4 immunotoxin M-T151 (IgG)-RTA | Cytotoxicity assay, Function study |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-033 | Human Anti-CD4 Recombinant Antibody (clone 17b); Fab Fragment | WB, ELISA, FuncS | Human Fab |
PFBL-034 | Mouse Anti-CD4 Recombinant Antibody (clone 2D5); Fab Fragment | Neut, ELISA, FuncS | Mouse Fab |
PFBL-035 | Mouse Anti-CD4 Recombinant Antibody (clone Q425); Fab Fragment | WB, ELISA, FuncS | Mouse Fab |
FAMAB-0007-CN-F(E) | Mouse Anti-CD4 Recombinant Antibody (clone CT4); Fab Fragment | FC | Mouse Fab |
FAMAB-0008-CN-F(E) | Mouse Anti-CD4 Recombinant Antibody (clone EP96); Fab Fragment | FC | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-161LC | Anti-Human CD4 Recombinant Antibody (gOKT4A-4) | ELISA | Humanized antibody |
TAB-168LC | Anti-Human CD4 Recombinant Antibody (TRX1) | ELISA | Humanized antibody |
TAB-171LC | Human Anti-CD4 Recombinant Antibody (TAB-171LC) | ELISA, FC, SPR | Humanized antibody |
TAB-172LC | Human Anti-CD4 Recombinant Antibody (TAB-172LC) | ELISA, Inhib | Human IgG |
TAB-161LC-S(P) | Anti-Human CD4 Recombinant Antibody scFv Fragment (gOKT4A-4) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-173LC-S(P) | Anti-Human CD4 Recombinant Antibody scFv Fragment (IgA F425-Alg8) | ELISA | |
TAB-174LC-S(P) | Mouse Anti-CD4 Recombinant Antibody; scFv Fragment (TAB-174LC-S(P)) | ELISA, FC, IH | Mouse scFv |
TAB-175LC-S(P) | Anti-Human CD4 Recombinant Antibody scFv Fragment (15A7) | FC, ELISA | |
TAB-176LC-S(P) | Anti-Human CD4 Recombinant Antibody scFv Fragment (14G7) | FC, ELISA | |
TAB-160LC-F(E) | Anti-Human CD4 Recombinant Antibody Fab Fragment (OKT4A) | ELISA |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-025LC | Recombinant Anti-Human CD4 Antibody (Fab glycosylation) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-352CQ | Mouse Anti-CD4 Recombinant Antibody (clone 13B8.2) | Block, ELISA, FC, IHC-Fr, WB | Mouse IgG1, κ |
NEUT-355CQ | Mouse Anti-CD4 Recombinant Antibody (clone RPA-T4) | FC, CyTOF, Block, IHC | Mouse IgG1, κ |
NEUT-357CQ | Rat Anti-CD4 Recombinant Antibody (clone MAB0810) | Block, Depletion, Stim | Rat IgG2b |
NEUT-358CQ | Rat Anti-CD4 Recombinant Antibody (clone RM4-5) | FC, CyTOF, Depletion, Block, IHC | Rat IgG2a, κ |
NEUT-359CQ | Rat Anti-CD4 Recombinant Antibody (clone YTS177) | Block | Rat IgG2a |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-353CQ | Mouse Anti-CD4 Recombinant Antibody (clone CBL976) | FC, Neut, IF, IHC | Mouse IgG1, κ |
NEUT-354CQ | Recombinant Mouse Anti-CD4 Antibody (CT-4) | Neut, FC, IHC, IHC-Fr, IHC-P, IP | IgG1, κ |
NEUT-356CQ | Mouse Anti-CD4 Recombinant Antibody (clone 3-4F4) | Neut, FC, IHC, IHC-Fr, IP, ICC | Mouse IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-0560 | Hi-Affi™ Rabbit Anti-CD4 Recombinant Antibody (clone DS560AB) | IHC-P | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0048CQ-S(P) | Mouse Anti-CD4 Recombinant Antibody (clone Leu3a); scFv Fragment | ELISA, FC | Mouse scFv |
HPAB-0758-CN-S(P) | Human Anti-CD4 Recombinant Antibody (clone Variant B); scFv Fragment | ELISA, FC | Human scFv |
HPAB-0759-CN-S(P) | Human Anti-CD4 Recombinant Antibody (clone Variant D); scFv Fragment | ELISA, FC | Human scFv |
HPAB-0135CQ-S(P) | Human Anti-CD4 Recombinant Antibody; scFv Fragment (HPAB-0135CQ-S(P)) | ELISA, FuncS | Human scFv |
HPAB-2059LY-S(P) | Mouse Anti-CD4 Recombinant Antibody; scFv Fragment (HPAB-2059LY-S(P)) | FC | Mouse scfv |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-039 | Afuco™ Anti-CD4 ADCC Recombinant Antibody (Zanolimumab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
AFC-TAB-164 | Afuco™ Anti-CD4 ADCC Recombinant Antibody (Priliximab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC | ADCC enhanced antibody |
AFC-TAB-260 | Afuco™ Anti-CD4 ADCC Recombinant Antibody (Tregalizumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF | ADCC enhanced antibody |
AFC-TAB-171 | Afuco™ Anti-CD4 ADCC Recombinant Antibody (Keliximab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
AFC-TAB-107 | Afuco™ Anti-CD4 ADCC Recombinant Antibody (Cedelizumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
There are currently no Customer reviews or questions for AGTO-G078E. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.