Mouse Anti-CD4 Recombinant Antibody Hexamer (VS-0924-YC116), CDC Enhanced (CAT#: VS-0924-YC116)

• Immunogen
• Human CD4 peptide, RFLPADQMNVADPQPLASCS

• Host Species
• Mouse

• Type
• Antibody hexamer

• Specificity
• Human CD4

• Species Reactivity
• Human

• Molecule Class
• ~ 900 kDa

• Applications
• WB, ELISA, IF, CDC

• Conjugate
• None

• Clonality
• Monoclonal

• Purification
• Protein G purified

• Purity
• >95% determined as SDS-PAGE and SEC-HPLC

• Aggregation
• <5%

• Buffer
• PBS, pH 7.4

• Preservative
• No preservatives

• Storage
• Store at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Avoid repeated freeze/thaw cycles.

• Alternative Names
• CD4 Molecule; T-Cell Surface Glycoprotein CD4; T-Cell Surface Antigen T4/Leu-3; CD4 Antigen (P55); CD4 Receptor; CD4 Antigen; CD4mut

• Gene ID
• 920

• UniProt ID
• P01730

• Long Name
• CD4 Molecule

• Sequence Similarities
• The Ig-like V-type domain mediates the interaction with MHCII.

• Post Translation Modifications
• Palmitoylation and association with LCK contribute to the enrichment of CD4 in lipid rafts. ( P01730-CD4_HUMAN )
  Phosphorylated by PKC; phosphorylation at Ser-433 plays an important role for CD4 internalization. ( P01730-CD4_HUMAN )
  Glycosylation at Asn296 and Asn325 ( NX_P01730 [NX_P01730-1] )
  Ubiquitination at Lys453 ( NX_P01730 [NX_P01730-1] )

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