Afuco™ Anti-CD4 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-039)

CAT#: AFC-TAB-039

This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to CD4. It is a human monoclonal antibody and an immunosuppressive drug. It is being developed for the treatment of rheumatoid arthritis, psoriasis, melanoma, cutaneous and peripheral T-cell lymphoma.

Gene Expression
Figure 1 IF staining of human cell line U-251 MG Figure 2 RNA cell line category: Group enriched (HEL, HL-60, NB-4, THP-1, U-937)

Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • ADCC enhanced antibody
  • Species Reactivity
  • Human
  • Applications
  • Neut, ELISA, IF, IP, FuncS, FC
  • Conjugate
  • Unconjugated
  • Trade name
  • Humax-Cd4
  • Generic Name
  • Zanolimumab
  • Related Disease
  • Cutaneous T cell lymphoma (CTCL)

Product Property

  • Purity
  • >95% by SDS-PAGE
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • CD4; CD4 molecule; CD4 antigen (p55), T cell surface glycoprotein CD4; T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); T-cell surface antigen T4/Leu-3; CD4mut;
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Breast cancer biomarkers at key points during disease progression
Increased accuracy
This antibody product has helped us increase the accuracy of our detections and measurements, contributing to higher quality data.
Breast cancer biomarkers at key points during disease progression
Highly specific
The high specificity of this antibody product has reduced background noise in our assays, leading to clearer and more interpretable results.
Breast cancer biomarkers at key points during disease progression
Quality control
The stringent quality control measures for this product ensure its reliability, making it a dependable choice for our experiments.

Q&As

  1. Can antibodies be employed on animals?

    A: Some antibodies can be used for veterinary purposes, however formulations that have been particularly formulated and tested for animal usage are recommended.

  2. What's the distinction between cloned and chimeric antibodies?

    A: Humanized antibodies are essentially human, with only the antigen-binding sites coming from a non-human species, whereas chimeric antibodies contain higher amounts of both human and non-human components.

  3. Do antibodies necessitate particular removal procedures?

    A: To avoid environmental contamination and maintain safety, follow local legislation and recommendations when disposing of biological products.

View the frequently asked questions answered by Creative Biolabs Support.

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Biosimilar Overview

Please refer to Zanolimumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Zanolimumab.

Related Diseases

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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Protocol & Troubleshooting

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

See other products for "Zanolimumab"

Anti-Human CD4 Recombinant Antibody (Zanolimumab)
Recombinant monoclonal antibody to CD4. Zanolimumab (expected trade name HuMax-CD4) is a human monoclonal antibody and an immunosuppressive drug. It is being developed for the treatment of rheumatoid arthritis, psoriasis, melanoma, cutaneous and peripheral T-cell lymphoma.
DrugMonitor™ Anti-Zanolimumab Antibody (VS-1224-YC1341)
Zanolimumab is a fully human monoclonal antibody directed against CD4. The DrugMonitor™ Anti-Zanolimumab Antibody (VS-1224-YC1341) is an anti-drug antibody (ADA) against Zanolimumab. This drug-based antibody is raised in mice immunized with the Zanolimumab. The anti-Zanolimumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Zanolimumab in samples.

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