Afuco™ Anti-CD4 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-039)
CAT#: AFC-TAB-039
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to CD4. It is a human monoclonal antibody and an immunosuppressive drug. It is being developed for the treatment of rheumatoid arthritis, psoriasis, melanoma, cutaneous and peripheral T-cell lymphoma.


Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- Neut, ELISA, IF, IP, FuncS, FC
- Conjugate
- Unconjugated
- Trade name
- Humax-Cd4
- Generic Name
- Zanolimumab
- Related Disease
- Cutaneous T cell lymphoma (CTCL)
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Customer Review
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Q&As
-
Can antibodies be employed on animals?
A: Some antibodies can be used for veterinary purposes, however formulations that have been particularly formulated and tested for animal usage are recommended.
-
What's the distinction between cloned and chimeric antibodies?
A: Humanized antibodies are essentially human, with only the antigen-binding sites coming from a non-human species, whereas chimeric antibodies contain higher amounts of both human and non-human components.
-
Do antibodies necessitate particular removal procedures?
A: To avoid environmental contamination and maintain safety, follow local legislation and recommendations when disposing of biological products.
View the frequently asked questions answered by Creative Biolabs Support.
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Biosimilar Overview
Please refer to Zanolimumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Zanolimumab.
Related Diseases
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Zanolimumab"
Anti-Human CD4 Recombinant Antibody (Zanolimumab)Recombinant monoclonal antibody to CD4. Zanolimumab (expected trade name HuMax-CD4) is a human monoclonal antibody and an immunosuppressive drug. It is being developed for the treatment of rheumatoid arthritis, psoriasis, melanoma, cutaneous and peripheral T-cell lymphoma.
DrugMonitor™ Anti-Zanolimumab Antibody (VS-1224-YC1341)Zanolimumab is a fully human monoclonal antibody directed against CD4. The DrugMonitor™ Anti-Zanolimumab Antibody (VS-1224-YC1341) is an anti-drug antibody (ADA) against Zanolimumab. This drug-based antibody is raised in mice immunized with the Zanolimumab. The anti-Zanolimumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Zanolimumab in samples.
See other products for "CD4"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-039 | Anti-Human CD4 Recombinant Antibody (Zanolimumab) | Neut, ELISA, IF, IP, FuncS, FC, IHC | IgG1 - kappa |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-G078E | Anti-CD4 immunotoxin M-T151 (IgG)-PE | Cytotoxicity assay, Function study | |
AGTO-G078R | Anti-CD4 immunotoxin M-T151 (IgG)-RTA | Cytotoxicity assay, Function study |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-033 | Human Anti-CD4 Recombinant Antibody (clone 17b); Fab Fragment | WB, ELISA, FuncS | Human Fab |
PFBL-034 | Mouse Anti-CD4 Recombinant Antibody Fab Fragment (PFBL-034) | Neut, ELISA, FuncS | Mouse Fab |
PFBL-035 | Mouse Anti-CD4 Recombinant Antibody (clone Q425); Fab Fragment | WB, ELISA, FuncS | Mouse Fab |
HPAB-0135CQ-F(E) | Human Anti-CD4 Recombinant Antibody; Fab Fragment (HPAB-0135CQ-F(E)) | ELISA, FuncS | Human Fab |
HPAB-0136CQ-F(E) | Mouse Anti-CD4 Recombinant Antibody; Fab Fragment (HPAB-0136CQ-F(E)) | ELISA, FuncS | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-160LC | Anti-Human CD4 Recombinant Antibody (OKT4A) | ELISA, WB | |
TAB-166LC | Anti-Human CD4 Recombinant Antibody (M-T412) | ELISA, Inhib | |
TAB-169LC | Rat Anti-CD4 Recombinant Antibody (TAB-169LC) | ELISA, FC, SPR | Rat IgG |
TAB-173LC | Anti-Human CD4 Recombinant Antibody (IgA F425-Alg8) | ELISA, Inhib | |
TAB-174LC | Mouse Anti-CD4 Recombinant Antibody (TAB-174LC) | ELISA, FC, IHC, Neut, FuncS | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-161LC | Anti-Human CD4 Recombinant Antibody (gOKT4A-4) | ELISA | Humanized antibody |
TAB-161LC-S(P) | Anti-Human CD4 Recombinant Antibody scFv Fragment (gOKT4A-4) | ELISA | Humanized antibody |
TAB-168LC-S(P) | Anti-Human CD4 Recombinant Antibody scFv Fragment (TRX1) | ELISA | Humanized antibody |
TAB-171LC-S(P) | Human Anti-CD4 Recombinant Antibody; scFv Fragment (TAB-171LC-S(P)) | ELISA, SPR | Humanized scFv |
TAB-172LC-S(P) | Human Anti-CD4 Recombinant Antibody; scFv Fragment (TAB-172LC-S(P)) | ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-162LC-S(P) | Anti-Human CD4 Recombinant Antibody scFv Fragment | ELISA | Chimeric antibody (mouse/human) |
TAB-164LC-S(P) | Monkey Anti-CD4 Recombinant Antibody; scFv Fragment (TAB-164LC-S(P)) | FC, SPR, ELISA | Monkey scFv |
TAB-165LC-S(P) | Monkey Anti-CD4 Recombinant Antibody; scFv Fragment (TAB-165LC-S(P)) | FC, SPR, ELISA | Monkey scFv |
TAB-167LC-S(P) | Anti-Human CD4 Recombinant Antibody scFv Fragment (cM-T412) | ELISA | Chimeric antibody (mouse/human) |
TAB-170LC-S(P) | Rat Anti-CD4 Recombinant Antibody; scFv Fragment (TAB-170LC-S(P)) | ELISA, SPR | Rat scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-025LC | Recombinant Anti-Human CD4 Antibody (Fab glycosylation) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-353CQ | Mouse Anti-CD4 Recombinant Antibody (clone CBL976) | FC, Neut, IF, IHC | Mouse IgG1, κ |
NEUT-354CQ | Recombinant Mouse Anti-CD4 Antibody (CT-4) | Neut, FC, IHC, IHC-Fr, IHC-P, IP | IgG1, κ |
NEUT-356CQ | Mouse Anti-CD4 Recombinant Antibody (clone 3-4F4) | Neut, FC, IHC, IHC-Fr, IP, ICC | Mouse IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-355CQ | Mouse Anti-CD4 Recombinant Antibody (clone RPA-T4) | FC, CyTOF, Block, IHC | Mouse IgG1, κ |
NEUT-357CQ | Rat Anti-CD4 Recombinant Antibody (clone MAB0810) | Block, Depletion, Stim | Rat IgG2b |
NEUT-358CQ | Rat Anti-CD4 Recombinant Antibody (clone RM4-5) | FC, CyTOF, Depletion, Block, IHC | Rat IgG2a, κ |
NEUT-359CQ | Rat Anti-CD4 Recombinant Antibody (clone YTS177) | Block | Rat IgG2a |
NEUT-360CQ | Rat Anti-CD4 Recombinant Antibody (clone GK1.5) | FC, Block, Costim, Depletion, IHC, IP | Rat IgG2b, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-0560 | Hi-Affi™ Rabbit Anti-CD4 Recombinant Antibody (clone DS560AB) | IHC-P | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0302LY-S(P) | Human Anti-CD4 Recombinant Antibody (clone TNX-355); scfv Fragment | ELISA | Humanized scfv |
HPAB-0303LY-S(P) | Human Anti-CD4 Recombinant Antibody (clone G4H); scfv Fragment | ELISA | Humanized scfv |
HPAB-0304LY-S(P) | Human Anti-CD4 Recombinant Antibody (clone G4D); scfv Fragment | ELISA | Humanized scfv |
HPAB-0305LY-S(P) | Human Anti-CD4 Recombinant Antibody (clone MV1); scfv Fragment | ELISA | Humanized scfv |
HPAB-2059LY-S(P) | Mouse Anti-CD4 Recombinant Antibody; scFv Fragment (HPAB-2059LY-S(P)) | FC | Mouse scfv |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-0303-CN | Rabbit Anti-CD4 Recombinant Antibody (clone CBACN-117) | WB, IF, IHC | Rabbit IgG |
FAMAB-1058CQ | Human Anti-CD4 Recombinant Antibody (clone DB81) | Inhib, FC | Human IgG1 |
FAMAB-1059CQ | Mouse Anti-CD4 Recombinant Antibody (clone 8A5) | WB, ELISA, IF | Mouse IgG1 |
FAMAB-1060CQ | Rat Anti-CD4 Recombinant Antibody (clone YNB46.1.8 (Campath-9H)) | FC, IHC, IHC-Fr | Rat IgG1 |
FAMAB-1061CQ | Human Anti-CD4 Recombinant Antibody (clone MT310) | IHC-P, IP, WB, FC, IF | Human IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-164 | Afuco™ Anti-CD4 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-164) | FuncS, IF, Neut, ELISA, FC | ADCC enhanced antibody |
AFC-TAB-260 | Afuco™ Anti-CD4 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-260) | ELISA, FC, IP, FuncS, IF | ADCC enhanced antibody |
AFC-TAB-171 | Afuco™ Anti-CD4 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-171) | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
AFC-TAB-107 | Afuco™ Anti-CD4 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-107) | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
AFC-TAB-146 | Afuco™ Anti-CD4 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-146) | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0724-YC759 | AbPlus™ Anti-Cd4 Magnetic Beads (VS-0724-YC759) | IP, Protein Purification |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0924-YC114 | Rat Anti-CD4 Recombinant Antibody Hexamer (VS-0924-YC114), CDC Enhanced | ELISA, FC, CDC | Antibody hexamer |
VS-0924-YC115 | Human Anti-CD4 Recombinant Antibody Hexamer (VS-0924-YC115), CDC Enhanced | ELISA, FC, ADCC, CDC, SPR | Antibody hexamer |
VS-0924-YC116 | Mouse Anti-CD4 Recombinant Antibody Hexamer (VS-0924-YC116), CDC Enhanced | WB, ELISA, IF, CDC | Antibody hexamer |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-1024-XY95 | Mouse Anti-NHP CD4 Recombinant Antibody (clone RIV7) | IF, FC | Mouse IgG2a, kappa |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0225-XY48 | CytoStream™ Mouse Anti-CD4 Recombinant Antibody (clone OKT4) | FC | Mouse IgG2b, kappa |
VS-0225-XY49 | CytoStream™ Mouse Anti-CD4 Recombinant Antibody (clone OX-35) | FC | Mouse IgG2a, kappa |
VS-0225-XY50 | CytoStream™ Rat Anti-CD4 Recombinant Antibody (clone RM4-4) | FC | Rat IgG2b, kappa |
VS-0225-XY51 | CytoStream™ Mouse Anti-CD4 Recombinant Antibody (clone KEN-4) | FC, Block, IHC, IP | Mouse IgG2a, kappa |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0325-FY64 | Human Anti-CD4 (clone TRX1) scFv-Fc Chimera | ELISA | Human IgG1, scFv-Fc |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0425-YC755 | Recombinant Anti-CD4 Vesicular Antibody, EV Displayed (VS-0425-YC755) | ELISA, FC, Neut, Cell-uptake |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0525-XY1178 | Anti-CD4 Immunohistochemistry Kit | IHC | |
VS-0525-XY1179 | Anti-Mouse CD4 Immunohistochemistry Kit | IHC | |
VS-0525-XY1180 | Anti-Human CD4 Immunohistochemistry Kit | IHC |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0525-YC204 | Recombinant Anti-CD4 (Domain 1 x Domain 2) Biparatopic Antibody, Tandem scFv | ELISA, FC, ICC, IF, IP, Neut | Tandem scFv |
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