Anti-Human TRAIL-R2 Recombinant Antibody (TAB-196) (CAT#: TAB-196)

Recombinant monoclonal antibody to TRAIL-R2. It is a monoclonal antibody for the treatment of cancer.

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SDS-PAGE

Figure 1 Anti-Human TRAIL-R2 Recombinant Antibody (TAB-196) in SDS-PAGE

Figure 1 Anti-Human TRAIL-R2 Recombinant Antibody (TAB-196) in SDS-PAGE

SDS-PAGE analysis of TAB-196 in reduced (Lane 1) and non-reduced (Lane 2) conditions. Gel stained for 30 minutes with Coomassie Blue. As a result, different β-mercaptoethanol-reduced proteins (Heavy chain and Light chain) migrate as about 50 kDa and 25 kDa, respectively.

The purity of TAB-196 was greater than 95% as determined by SDS-PAGE.

SEC-HPLC

Figure 2 Anti-Human TRAIL-R2 Recombinant Antibody (TAB-196) in HPLC

Figure 2 Anti-Human TRAIL-R2 Recombinant Antibody (TAB-196) in HPLC

The purity of TAB-196 was greater than 95% as determined by SEC-HPLC.

WB

Figure 3 Anti-Human TRAIL-R2 Recombinant Antibody (TAB-196) in WB

Figure 3 Anti-Human TRAIL-R2 Recombinant Antibody (TAB-196) in WB

Western blot analysis of TAB-196 was performed by loading Recombinant Human TRAIL-R2.

TAB-196 incubation concentration: 2 ng/μL.
The secondary antibody: HRP-anti-human IgG
Lane 1: Reducing Antigen (0.1 μg)
Lane 2: Reducing Antigen (0.3 μg)
Lane 3: Reducing Antigen (0.6 μg)

ELISA

Figure 4 Anti-Human TRAIL-R2 Recombinant Antibody (TAB-196) in ELISA

Figure 4 Anti-Human TRAIL-R2 Recombinant Antibody (TAB-196) in ELISA

ELISA analysis of TAB-196 was performed by coating with Recombinant Human TRAIL-R2.

The secondary antibody: HRP-anti-human IgG


Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Mouse
  • Derivation
  • Humanized (from mouse)
  • Type
  • IgG1
  • Specificity
  • Tested positive against native human antigen.
  • Species Reactivity
  • Human
  • Applications
  • IF, IP, Neut, FuncS, ELISA, FC, ICC
  • MW
  • 144.6 kDa
  • Related Disease
  • Unknown

Product Property

  • Purity
  • >95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Applications

  • Application Notes
  • The TNFRSF10B antibody has been reported in applications of WB, Inhib, FC, IHC.

Target

  • Alternative Names
  • Tigatuzumab;918127-53-4;CS-1008;TRA-8;CS-1008;TNFRSF10B;tumor necrosis factor receptor superfamily, member 10b;tumor necrosis factor receptor superfamily member 10B;CD262;DR5;KILLER;TRAIL R2;TRICK2A;TRICKB;Fas-like protein;death receptor 5;cytotoxic TRAIL

Related Resources

  • Biosimilar Overview
Please refer to Tigatuzumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Tigatuzumab.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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