Afuco™ Anti-Human TIE1 ADCC Recombinant Antibody (DX-2240), ADCC Enhanced (CAT#: AFC-586CL)
Anti-TIE1 ADCC Enhanced Antibody (DX-2240) is an ADCC enhanced antibody produced by our Afuco™ platform. DX-2240 is a fully human monoclonal antibody that targets the Tie-1 receptor on tumor blood vessels and has therapeutic potential in numerous oncology indications. In preclinical animal models, DX-2240 has demonstrated activity against a broad range of solid tumor types.
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RNA Expression
Figure 1 RNA cell line category: Group enriched (EFO-21, HUVEC TERT2, TIME)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000066056-TIE1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000066056-TIE1
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE
- Storage
- Store at -20°C. Open under aseptic conditions.
Target
- Alternative Names
- TIE1; tyrosine kinase with immunoglobulin-like and EGF-like domains 1; TIE; JTK14; tyrosine-protein kinase receptor Tie-1; tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 1
- Gene ID
- 7075
- UniProt ID
- B4DTW8
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "TIE1"
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-608CL | Human Anti-TIE1 Recombinant Antibody (TAB-608CL) | ELISA | Human IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0314CQ | Human Anti-TIE1 Recombinant Antibody (HPAB-0314CQ) | ELISA, FC, WB, IHC, IF, Inhib, Agonist | Human IgG1, κ |
| HPAB-0315CQ | Human Anti-TIE1 Recombinant Antibody (HPAB-0315CQ) | ELISA, FC, WB, IHC, IF, Block | Human IgG1, κ |
| HPAB-0316CQ | Human Anti-TIE1 Recombinant Antibody (HPAB-0316CQ) | ELISA, FC, WB, IHC, IF, Block | Human IgG1, κ |
| HPAB-0317CQ | Human Anti-TIE1 Recombinant Antibody (HPAB-0317CQ) | ELISA, FC, FuncS | Human IgG1, κ |
| MRO-2223-CN | Rabbit Anti-TIE1 Polyclonal Antibody (MRO-2223-CN) | WB, IF, IHC | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0314CQ-F(E) | Human Anti-TIE1 Recombinant Antibody; Fab Fragment (HPAB-0314CQ-F(E)) | ELISA, FC, WB, IHC, IF, Agonist | Human Fab |
| HPAB-0315CQ-F(E) | Human Anti-TIE1 Recombinant Antibody; Fab Fragment (HPAB-0315CQ-F(E)) | ELISA, FC, WB, IHC, IF, Block | Human Fab |
| HPAB-0316CQ-F(E) | Human Anti-TIE1 Recombinant Antibody; Fab Fragment (HPAB-0316CQ-F(E)) | ELISA, FC, WB, IHC, IF, Block | Human Fab |
| HPAB-0317CQ-F(E) | Human Anti-TIE1 Recombinant Antibody; Fab Fragment (HPAB-0317CQ-F(E)) | ELISA, FC, FuncS | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0314CQ-S(P) | Human Anti-TIE1 Recombinant Antibody; scFv Fragment (HPAB-0314CQ-S(P)) | ELISA, FC, WB, IHC, IF, Agonist | Human scFv |
| HPAB-0315CQ-S(P) | Human Anti-TIE1 Recombinant Antibody; scFv Fragment (HPAB-0315CQ-S(P)) | ELISA, FC, WB, IHC, IF, Block | Human scFv |
| HPAB-0316CQ-S(P) | Human Anti-TIE1 Recombinant Antibody; scFv Fragment (HPAB-0316CQ-S(P)) | ELISA, FC, WB, IHC, IF, Block | Human scFv |
| HPAB-0317CQ-S(P) | Human Anti-TIE1 Recombinant Antibody; scFv Fragment (HPAB-0317CQ-S(P)) | ELISA, FC, FuncS | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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