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    Anti-Human VEGFA Recombinant Antibody scFv Fragment (TAB-009ML) (CAT#: TAB-009ML)

    Recombinant monoclonal antibody to VEGFA. It is a human monoclonal antibody that can be potentially used in the treatment of Age-related macular degeneration (AMD), neovascular (wet).

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 Cerebral cortex
    Figure 1 Cerebral cortex
    (Neuronal cells
    Staining:

    Medium

    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/
    membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39240/82308_B_7_5.jpg
    Figure 2 Thyroid gland
    Figure 2 Thyroid gland
    (Glandular cells
    Staining:

    Medium

    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/
    membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39240/82308_B_1_5.jpg
    Figure 3 Colon
    Figure 3 Colon
    (Glandular cells
    Staining:

    High

    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/
    membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39240/82308_A_7_3.jpg
    Figure 4 Liver
    Figure 4 Liver
    (Cholangiocytes
    Staining:

    Medium

    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/
    membranous
    Hepatocytes
    Staining:

    High

    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/
    membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39240/82308_A_8_4.jpg
    Figure 5 Kidney
    Figure 5 Kidney
    (Cells in glomeruli
    Staining:

    Medium

    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/
    membranous
    Cells in tubules
    Staining:

    Medium

    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/
    membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39240/82308_A_9_5.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Leydig cells
    Staining:

    High

    Intensity: Strong
    Quantity:>75%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39240/82308_A_5_6.jpg
    Figure 7 Lymph node
    Figure 7 Lymph node
    (Non-germinal center cells
    Staining:

    Medium

    Intensity: Strong
    Quantity: <25%
    Location: Cytoplasmic/
    membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39240/82308_A_7_8.jpg
    RNA Expression
    Figure 8 RNA cell line category: Cell line enhanced (hTERT-RPE1, U-87 MG)
    Figure 8 RNA cell line category: Cell line enhanced (hTERT-RPE1, U-87 MG)
    (Cell lines ordered by descending RNA expression order.)
    * https://v21.proteinatlas.org/ENSG00000112715-VEGFA
    Figure 8 RNA cell line category: Cell line enhanced (hTERT-RPE1, U-87 MG)
    Figure 8 RNA cell line category: Cell line enhanced (hTERT-RPE1, U-87 MG)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000112715-VEGFA

    Specifications

    • Immunogen
    • The details of the immunogen for this antibody are not available.
    • Host Species
    • Human
    • Derivation
    • Humanized
    • Type
    • scFv, κ
    • Specificity
    • Human VEGFA
    • Species Reactivity
    • Human
    • Applications
    • Used for immunoassay techniques such as: Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Immunofluorescence; Immunoprecipitation; Flow Cytometry; Inhibition
    • Conjugate
    • Unconjugated
    • Related Disease
    • Age-related macular degeneration (AMD), neovascular (wet)

    Product Property

    • Purity
    • > 95% as determined by SDS-PAGE
    • Storage
    • Store at -20°C for long-term storage. Avoid freeze/thaw cycles.

    Target

    • Alternative Names
    • Vascular endothelial growth factor A; VEGF-A; VEGF

    Related Resources

    • Biosimilar Overview
    Please refer to Brolucizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Brolucizumab.

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "VEGFA"

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    CAT Product Name Application Type
    TAB-H73 Anti-Human VEGFA Recombinant Antibody (TAB-H73) WB, FC, IP, ELISA, Neut, FuncS, IF VH - C-kappa - CH2 - CH3 _ V-lambda - CH1 _ H-GAMMA-1 _ L-kappa
    TAB-011 Anti-Human VEGF Recombinant Antibody (Bevacizumab) FC, IP, ELISA, Neut, FuncS, IF, ICC IgG1 - kappa
    TAB-012-F(E) Anti-Human VEGF Recombinant Antibody Fab Fragment (TAB-012-F(E)) IP, IF, FuncS, FC, Neut, ELISA, IHC Fab - G1 - kappa
    TAB-307CQ Human Anti-VEGFA Recombinant Antibody (TAB-307CQ) Inhib Human IgG
    TAB-307CQ-F(E) Human Anti-VEGFA Recombinant Antibody; Fab Fragment (TAB-307CQ-F(E)) ELISA, Neut Humanized Fab

    Customer Reviews and Q&As

    Customer Review Q&As

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    Versatile Research Tool
    The scFv fragment's high specificity for VEGFA makes it an incredibly versatile tool in our angiogenesis studies. Its multiple application areas, from ELISA to flow cytometry, allow us to gain a comprehensive understanding of VEGFA dynamics in various biological systems.

    Aiding in AMD Research
    This scFv fragment has become a valuable resource in our age-related macular degeneration studies, offering insights into VEGFA's role in disease mechanisms and the potential development of targeted therapies.

    Cite This Product

    To accurately reference this product in your publication, please use the following citation information:

    (Creative Biolabs Cat# TAB-009ML, RRID: AB_3111738)

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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