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  • PE-B*07:02/Human MS4A1 (RPKSNIVLL) MHC Tetramer

PE-B*07:02/Human MS4A1 (RPKSNIVLL) MHC Tetramer (CAT#: MHC-LC4347)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human MS4A1 of peptide RPKSNIVLL covering 222-230 and B*07:02 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

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Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line REH
Figure 1 IF staining of human cell line REH
(Immunofluorescent staining of human cell line REH shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/1778_G3_5_selected.jpg
Figure 2 IF staining of human cell line A-431
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/201_H5_1_red_green.jpg
Figure 3 IF staining of human cell line U-2 OS
Figure 3 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/202_H5_1_red_green.jpg
Normal Tissue
Figure 4 Colon
Figure 4 Colon
(Mucosal lymphoid cells
Staining:Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/39081_A_7_3.jpg
Figure 5 Bone marrow
Figure 5 Bone marrow
(Hematopoietic cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/39081_B_4_4.jpg
Figure 6 Lymph node
Figure 6 Lymph node
(Germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/39081_A_7_8.jpg
RNA Expression
Figure 7 RNA cell line category: Group enriched (Daudi, U-698)
Figure 7 RNA cell line category: Group enriched (Daudi, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000156738-MS4A1

Specifications

  • Allele
  • B*07:02
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • MS4A1
  • Antigen Species
  • Human
  • Peptide
  • RPKSNIVLL
  • Range
  • 222-230
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008]
  • Alternative Names
  • MS4A1; B-lymphocyte antigen CD20; B1; S7; Bp35; CD20; CVID5; LEU-16

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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