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    Afuco™ Anti-MS4A1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-016) (CAT#: AFC-TAB-016)

    This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to Human CD20. It is a chimeric monoclonal antibody against the protein CD20, which is primarily found on the surface of immune system B cells (this should not be confused with pancreatic β- or beta cells).

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    • Conjugation:

    • Endotoxin:

    • Purity:

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    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line REH
    Figure 1 IF staining of human cell line REH
    (Immunofluorescent staining of human cell line REH shows localization to nucleoplasm & plasma membrane.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/1778_G3_5_selected.jpg
    Figure 2 IF staining of human cell line A-431
    Figure 2 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & plasma membrane.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/201_H5_1_red_green.jpg
    Figure 3 IF staining of human cell line U-2 OS
    Figure 3 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & plasma membrane.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/202_H5_1_red_green.jpg
    Normal Tissue
    Figure 4 Colon
    Figure 4 Colon
    (Mucosal lymphoid cells
    Staining:Medium
    Intensity: Strong
    Quantity: <25%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/39081_A_7_3.jpg
    Figure 5 Bone marrow
    Figure 5 Bone marrow
    (Hematopoietic cells
    Staining:Medium
    Intensity: Strong
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/39081_B_4_4.jpg
    Figure 6 Lymph node
    Figure 6 Lymph node
    (Germinal center cells
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining:Medium
    Intensity: Strong
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/39081_A_7_8.jpg
    RNA Expression
    Figure 7 RNA cell line category: Group enriched (Daudi, U-698)
    Figure 7 RNA cell line category: Group enriched (Daudi, U-698)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000156738-MS4A1

    Specifications

    • Immunogen
    • Human lymphoblastoid cell line SB
    • Host Species
    • Chimeric
    • Derivation
    • Chimeric (mouse/human)
    • Type
    • ADCC enhanced antibody
    • Species Reactivity
    • Human
    • Applications
    • IF, IP, Neut, FuncS, ELISA, FC
    • Conjugate
    • Unconjugated
    • Trade name
    • Rituximab
    • Generic Name
    • Rituximab
    • Related Disease
    • Wegener's Granulomatosis (WG) and Microscopic Polygamiitis (MPA), in combination with glucocorticoides

    Product Property

    • Purity
    • >95% by SDS-PAGE
    • Storage
    • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Target

    • Alternative Names
    • MS4A1; membrane-spanning 4-domains, subfamily A, member 1; CD20; B-lymphocyte antigen CD20; B1; Bp35; CD20 antigen; CD20 receptor; leukocyte surface antigen Leu-16

    Related Resources

    • Biosimilar Overview
    Please refer to Rituximab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Rituximab.

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "Rituximab"

    Anti-Human CD20 Recombinant Antibody (Rituximab)
    Recombinant monoclonal antibody to Human CD20. Rituximab (trade names rituximab and rituximab) is a chimeric monoclonal antibody against the protein CD20, which is primarily found on the surface of immune system B cells (this should not be confused with pancreatic β- or beta cells). Rituximab destroys B cells and is therefore used to treat diseases which are characterized by excessive numbers of B cells, overactive B cells, or dysfunctional B cells. This includes many lymphomas, leukemias, transplant rejection, and autoimmune disorders.

    See other products for "MS4A1"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    Chimeric Antibody Products Humanized Antibody Products Human Antibody Products Mouse Antibody Products Fc Glycosylation Antibody Products Low- or Non-fucosylated Oligosaccharide Antibody Products Hyper-galactosylated Antibody Products High-mannose Glycoform Antibody Products Deglycosylated Antibody Products MHC Tetramer Products for Cancer Neutralizing Antibody Products Rabbit Monoclonal Antibody Products IgG Antibody Products Fab Antibody Products ScFv Antibody Products Single Domain Antibody Products ADCC Enhanced Antibody Products Antibody Magnetic Beads Hexamer Antibody Products Non-Human Primate (NHP) Antibody Products ScFv-Fc Chimera Products Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    TAB-016 Anti-Human CD20 Recombinant Antibody (Rituximab) IF, IP, Neut, FuncS, ELISA, FC, WB IgG1 - kappa
    TAB-1633CL Anti-Human MS4A1 Recombinant Antibody (ch1F5) FC, Apop, CDC, ADCC, Inhib Chimeric antibody (mouse/human)
    TAB-1634CL Anti-Human MS4A1 Recombinant Antibody (ch1F5-DXL) FC, Apop, CDC, ADCC, Inhib Chimeric antibody (mouse/human)
    TAB-1656CL Anti-Human MS4A1 Recombinant Antibody (ch2B8) FC, CMCD, ADCC, Activ, Inhib, Depletion Chimeric antibody (mouse/human)
    PABX-026 Recombinant Human Anti-CD20 Antibody (C2H7) FuncS IgG

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    Cite This Product

    To accurately reference this product in your publication, please use the following citation information:

    (Creative Biolabs Cat# AFC-TAB-016, RRID: AB_3111282)

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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