MS4A1
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: IF, IP, Neut, FuncS, ELISA, FC, WB
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- Anti-CD20 Antibody-Cytokine Fusion Protein, IgG-IL2 (ACFP-SH132)
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- Target: CD20
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Chimeric (Human-Mouse)
- Cytokine 1 Species: Human
- Molecule Class: L Kappa; IgG1-IL2
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- Target: CD20
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Chimeric (Human-Mouse)
- Cytokine 1 Species: Human
- Molecule Class: L Kappa; IgG1-IL2
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1
- Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: WB, IF, FuncS
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- Anti-Human MS4A1 Recombinant Antibody scFv Fragment (ch1F5) (TAB-1633CL-S(P))
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: FC
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- Anti-Human MS4A1 Recombinant Antibody scFv Fragment (ch1F5-DXL) (TAB-1634CL-S(P))
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: FC, Apop, CDC, ADCC, Inhib
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- Anti-Human MS4A1 Recombinant Antibody scFv Fragment (BVX20) (TAB-1635CL-S(P))
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- Derivation: Humanized
- Type: Humanized antibody
- Application: Inhib
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- Human Anti-MS4A1 Recombinant Antibody; scFv Fragment (TAB-1636CL-S(P)) (TAB-1636CL-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ADCC, CDC
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- Human Anti-MS4A1 Recombinant Antibody; scFv Fragment (TAB-1637CL-S(P)) (TAB-1637CL-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ADCC, CDC
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- Human Anti-MS4A1 Recombinant Antibody; scFv Fragment (TAB-1638CL-S(P)) (TAB-1638CL-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ADCC, CDC
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- Human Anti-MS4A1 Recombinant Antibody; scFv Fragment (TAB-1639CL-S(P)) (TAB-1639CL-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ADCC, CDC, Apop
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- Human Anti-MS4A1 Recombinant Antibody; scFv Fragment (TAB-1640CL-S(P)) (TAB-1640CL-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ADCC, CDC, Apop, FuncS
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- Human Anti-MS4A1 Recombinant Antibody; scFv Fragment (TAB-1641CL-S(P)) (TAB-1641CL-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ADCC, CDC, Apop
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- Anti-Human MS4A1 Recombinant Antibody Fab Fragment (ch1F5) (TAB-1633CL-F(E))
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: FC
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- Anti-Human MS4A1 Recombinant Antibody Fab Fragment (ch1F5-DXL) (TAB-1634CL-F(E))
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: FC, Apop, CDC, ADCC, Inhib
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- Anti-Human MS4A1 Recombinant Antibody Fab Fragment (BVX20) (TAB-1635CL-F(E))
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- Derivation: Humanized
- Type: Humanized antibody
- Application: Inhib
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- Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1636CL-F(E)) (TAB-1636CL-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ADCC, CDC
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- Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1637CL-F(E)) (TAB-1637CL-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ADCC, CDC
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- Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1638CL-F(E)) (TAB-1638CL-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ADCC, CDC
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- Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1639CL-F(E)) (TAB-1639CL-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ADCC, CDC, Apop
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- Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1640CL-F(E)) (TAB-1640CL-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ADCC, CDC, Apop, FuncS
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- Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1641CL-F(E)) (TAB-1641CL-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ADCC, CDC, Apop
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- Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1642CL-F(E)) (TAB-1642CL-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ADCC, CDC
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- Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1643CL-F(E)) (TAB-1643CL-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ADCC, CDC
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- Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1644CL-F(E)) (TAB-1644CL-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ADCC, CDC
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- Anti-Human MS4A1 Recombinant Antibody Fab Fragment (2.1.2) (TAB-1645CL-F(E))
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- Type: Fully human antibody
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- Anti-Human MS4A1 Recombinant Antibody Fab Fragment (1.1.2) (TAB-1646CL-F(E))
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- Type: Fully human antibody
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- Anti-Human MS4A1 Recombinant Antibody Fab Fragment (1.5.3) (TAB-1647CL-F(E))
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- Type: Fully human antibody
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- Anti-MS4A1 Recombinant Antibody Fab Fragment (MEDI-552) (TAB-1648CL-F(E))
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- Application: Inhib
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- Anti-Human MS4A1 Recombinant Antibody Fab Fragment (BLX-301) (TAB-1649CL-F(E))
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- Derivation: Humanized
- Type: Humanized antibody
- Application: Inhib
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- Anti-Human MS4A1 Recombinant Antibody Fab Fragment (1F5RHA) (TAB-1650CL-F(E))
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA
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- Anti-Human MS4A1 Recombinant Antibody Fab Fragment (1F5RHB) (TAB-1651CL-F(E))
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA
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- Anti-Human MS4A1 Recombinant Antibody Fab Fragment (1F5RKA11) (TAB-1652CL-F(E))
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Humanized IgG1, κ
- Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: FC, Inhib
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: FC, IP, ELISA, Neut, FuncS, IF, IHC
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- Anti-Human CD20 Recombinant Antibody (TAB-207)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
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- Anti-Human MS4A1 Recombinant Antibody (ch1F5) (TAB-1633CL)
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: FC, Apop, CDC, ADCC, Inhib
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- Anti-Human MS4A1 Recombinant Antibody (ch1F5-DXL) (TAB-1634CL)
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: FC, Apop, CDC, ADCC, Inhib
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- Anti-Human MS4A1 Recombinant Antibody (BVX20) (TAB-1635CL)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: Inhib
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- Human Anti-MS4A1 Recombinant Antibody (TAB-1636CL) (TAB-1636CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ADCC, CDC
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- Human Anti-MS4A1 Recombinant Antibody (TAB-1637CL) (TAB-1637CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ADCC, CDC
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- Human Anti-MS4A1 Recombinant Antibody (TAB-1638CL) (TAB-1638CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ADCC, CDC
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- Human Anti-MS4A1 Recombinant Antibody (TAB-1639CL) (TAB-1639CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ADCC, CDC, Apop
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- Human Anti-MS4A1 Recombinant Antibody (TAB-1640CL) (TAB-1640CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ADCC, CDC, Apop, FuncS
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- Human Anti-MS4A1 Recombinant Antibody (TAB-1641CL) (TAB-1641CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ADCC, CDC, Apop
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- Human Anti-MS4A1 Recombinant Antibody (TAB-1642CL) (TAB-1642CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ADCC, CDC
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- Human Anti-MS4A1 Recombinant Antibody (TAB-1643CL) (TAB-1643CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ADCC, CDC, Apop
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- Human Anti-MS4A1 Recombinant Antibody (TAB-1644CL) (TAB-1644CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ADCC, CDC, Apop
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- Anti-Human MS4A1 Recombinant Antibody (2.1.2) (TAB-1645CL)
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- Type: Fully human antibody
- Application: Cyt, FuncS
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- Anti-Human MS4A1 Recombinant Antibody (1.1.2) (TAB-1646CL)
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- Type: Fully human antibody
- Application: Cyt, FuncS
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- Anti-Human MS4A1 Recombinant Antibody (1.5.3) (TAB-1647CL)
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- Type: Fully human antibody
- Application: Cyt, FuncS
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- Anti-MS4A1 Recombinant Antibody (MEDI-552) (TAB-1648CL)
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- Application: Inhib
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- Anti-Human MS4A1 Recombinant Antibody (1F5RHA) (TAB-1650CL)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA
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- Anti-Human MS4A1 Recombinant Antibody (1F5RHB) (TAB-1651CL)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA
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- Anti-Human MS4A1 Recombinant Antibody (1F5RKA11) (TAB-1652CL)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA
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- Anti-Human MS4A1 Recombinant Antibody (1F5RKB12) (TAB-1653CL)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA
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- Human Anti-MS4A1 Recombinant Antibody (TAB-1654CL) (TAB-1654CL)
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- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: FC, Apop
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- Anti-Human MS4A1 Recombinant Antibody (ch2B8) (TAB-1656CL)
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: FC, CMCD, ADCC, Activ, Inhib, Depletion
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- Human Anti-MS4A1 Recombinant Antibody; scFv Fragment (TAB-0001CL-S(P)) (TAB-0001CL-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Anti-Human MS4A1 Recombinant Antibody scFv Fragment (1F5) (TAB-1632CL-S(P))
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- Application: FC
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- Recombinant Anti-human MS4A1 VHH Single Domain Antibody (NAB-913-sdAb)
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- Species Reactivity: Human
- Type: Llama VHH
- Application: IP, FC, ChiP, Neut
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- Mouse Anti-MS4A1 Recombinant Antibody (TAB-1657CL) (TAB-1657CL)
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- Application: Apop, FuncS
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- Mouse Anti-MS4A1 Recombinant Antibody (TAB-1658CL) (TAB-1658CL)
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- Application: Apop, FuncS
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- Mouse Anti-MS4A1 Recombinant Antibody (TAB-1659CL) (TAB-1659CL)
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- Application: Apop, FuncS
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- Mouse Anti-MS4A1 Recombinant Antibody (TAB-1660CL) (TAB-1660CL)
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- Application: Apop, FuncS
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- Mouse Anti-MS4A1 Recombinant Antibody (TAB-1661CL) (TAB-1661CL)
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- Application: Apop, FuncS
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- Mouse Anti-MS4A1 Recombinant Antibody (TAB-1662CL) (TAB-1662CL)
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- Application: Apop, FuncS
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- Mouse Anti-MS4A1 Recombinant Antibody (TAB-1663CL) (TAB-1663CL)
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- Application: Apop, FuncS
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- Mouse Anti-MS4A1 Recombinant Antibody (TAB-1664CL) (TAB-1664CL)
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- Application: Apop, FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG2a - lambda
- Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab - G2b - kappa
- Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: ELISA, IP, FC, FuncS, IF, Neut
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- Target: CD20
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Chimeric (Human-Mouse)
- Cytokine 1 Species: Human
- Molecule Class: scFv-Fc-IL2
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- Anti-Human MS4A1 Recombinant Antibody Fab Fragment (1F5) (TAB-1632CL-F(E))
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- Application: FC
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: WB, IF, FuncS
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- Anti-Human MS4A1 Recombinant Antibody (1F5) (TAB-1632CL)
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- Application: FC
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, IF, FuncS
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB
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- Host Species: Human
- Specificity: Human
- Type: Humanized antibody
- Classification: Fc glycosylation/Non fucosylated
- Glycosylation site: Asn297 in Fc region
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- Host Species: Human
- Specificity: Human
- Type: Humanized antibody
- Classification: Fc glycosylation/Non fucosylated
- Glycosylation site: Asn297 in Fc region
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- Anti-CD20 (clone hA20)-SN-38 ADC (ADC-125CL)
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- Target: CD20
- Drug: SN-38 (7-ethyl-10-hydroxycamptothecin)
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- Anti-CD20-CL2A-SN-38 ADC (ADC-021LCT)
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- Target: CD20
- Linker: CL2A
- Drug: SN-38 (7-ethyl-10-hydroxycamptothecin)
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- Anti-CD20 (clone Batl206)-SMCC-MDC ADC (ADC-160CL)
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- Target: CD20
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: MDC (maytansinol)
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- Anti-CD20-CL2E-SN-38 ADC (ADC-022LCT)
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- Target: CD20
- Linker: CL2E
- Drug: SN-38 (7-ethyl-10-hydroxycamptothecin)
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- Anti-CD20 (1F5)-vcMMAE ADC (ADC-023LCT)
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- Target: CD20
- Linker: VC (valine-citrulline)
- Drug: MMAE (Monomethyl auristatin E)
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- Anti-CD20 (rituximab)-vcMMAE ADC (ADC-024LCT)
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- Target: CD20
- Linker: VC (valine-citrulline)
- Drug: MMAE (Monomethyl auristatin E)
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- Anti-CD20-SPP-DM1 ADC (ADC-185LZY)
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- Target: CD20
- Linker: SPP (N-succinimidyl-4-(2-pyridyldithio)pentanoate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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- Anti-CD20-MCC-DM1 ADC (ADC-186LZY)
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- Target: CD20
- Linker: MCC (Maleimidomethyl cyclohexane-1-carboxylate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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- Anti-CD20-mc-vc-PABC-MMAE ADC (ADC-187LZY)
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- Target: CD20
- Linker: mc-VC-PABC (maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
- Drug: MMAE (monomethyl auristatin E)
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- Anti-CD20-mc-MMAF ADC (ADC-188LZY)
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- Target: CD20
- Linker: mc (maleimidocaproyl)
- Drug: MMAF (monomethyl auristatin F)
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein.
