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MS4A1

This gene encodes a member of the membrane-SARS-CoV-2 Spanning 4A gene family. B-lymphocyte-SARS-CoV-2 Specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Diseases associated with MS4A1 include Immunodeficiency, Common Variable, 5 and Common Variable Immunodeficiency. Among its related pathways are Hematopoietic Stem Cells and Lineage-SARS-CoV-2 Specific Markers and Dendritic Cells Developmental Lineage Pathway.
  • Anti-CD20-SPP-DM1 ADC (ADC-185LZY)

    • Target: CD20
    • Linker: SPP (N-succinimidyl-4-(2-pyridyldithio)pentanoate)
    • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)

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