MS4A1
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: IF, IP, Neut, FuncS, ELISA, FC, WB
- Anti-CD20 Antibody-Cytokine Fusion Protein, IgG-IL2 (ACFP-SH132)
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- Target: CD20
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Chimeric (Human-Mouse)
- Cytokine 1 Species: Human
- Molecule Class: L Kappa; IgG1-IL2
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- Target: CD20
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Chimeric (Human-Mouse)
- Cytokine 1 Species: Human
- Molecule Class: L Kappa; IgG1-IL2
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1
- Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
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- Derivation: Human
- Species Reactivity: Human
- Type: Human IgG1,κ
- Application: WB, ELISA, FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA, FuncS
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- Derivation: Human
- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA, FuncS
- Human Anti-MS4A1 Recombinant Antibody (TAB-0001CL) (TAB-0001CL)
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- Derivation: Human
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, ADCC, CDC
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: WB, IF, FuncS
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1, κ
- Application: WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC, Activ, Agonist, IF, WB, Cyt, FuncS
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Humanized IgG1, κ
- Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG3 - kappa
- Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: FC, Inhib
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: FC, IP, ELISA, Neut, FuncS, IF, IHC
- Anti-Human CD20 Recombinant Antibody (TAB-207)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Derivation: Humanized
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Anti-Human MS4A1 Recombinant Antibody (ch1F5) (TAB-1633CL)
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: FC, Apop, CDC, ADCC, Inhib
- Anti-Human MS4A1 Recombinant Antibody (ch1F5-DXL) (TAB-1634CL)
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: FC, Apop, CDC, ADCC, Inhib
- Anti-Human MS4A1 Recombinant Antibody (BVX20) (TAB-1635CL)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: Inhib
- Human Anti-MS4A1 Recombinant Antibody (TAB-1636CL) (TAB-1636CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ADCC, CDC
- Human Anti-MS4A1 Recombinant Antibody (TAB-1637CL) (TAB-1637CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ADCC, CDC
- Human Anti-MS4A1 Recombinant Antibody (TAB-1638CL) (TAB-1638CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ADCC, CDC
- Human Anti-MS4A1 Recombinant Antibody (TAB-1639CL) (TAB-1639CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ADCC, CDC, Apop
- Human Anti-MS4A1 Recombinant Antibody (TAB-1640CL) (TAB-1640CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ADCC, CDC, Apop, FuncS
- Human Anti-MS4A1 Recombinant Antibody (TAB-1641CL) (TAB-1641CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ADCC, CDC, Apop
- Human Anti-MS4A1 Recombinant Antibody (TAB-1642CL) (TAB-1642CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ADCC, CDC
- Human Anti-MS4A1 Recombinant Antibody (TAB-1643CL) (TAB-1643CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ADCC, CDC, Apop
- Human Anti-MS4A1 Recombinant Antibody (TAB-1644CL) (TAB-1644CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ADCC, CDC, Apop
- Anti-Human MS4A1 Recombinant Antibody (2.1.2) (TAB-1645CL)
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- Type: Fully human antibody
- Application: Cyt, FuncS
- Anti-Human MS4A1 Recombinant Antibody (1.1.2) (TAB-1646CL)
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- Type: Fully human antibody
- Application: Cyt, FuncS
- Anti-Human MS4A1 Recombinant Antibody (1.5.3) (TAB-1647CL)
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- Type: Fully human antibody
- Application: Cyt, FuncS
- Anti-MS4A1 Recombinant Antibody (MEDI-552) (TAB-1648CL)
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- Application: Inhib
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- Derivation: Humanized
- Type: Humanized antibody
- Application: Inhib
- Anti-Human MS4A1 Recombinant Antibody (1F5RHA) (TAB-1650CL)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA
- Anti-Human MS4A1 Recombinant Antibody (1F5RHB) (TAB-1651CL)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA
- Anti-Human MS4A1 Recombinant Antibody (1F5RKA11) (TAB-1652CL)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA
- Anti-Human MS4A1 Recombinant Antibody (1F5RKB12) (TAB-1653CL)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA
- Human Anti-MS4A1 Recombinant Antibody (TAB-1654CL) (TAB-1654CL)
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- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: FC, Apop
- Anti-Human MS4A1 Recombinant Antibody (ch2B8) (TAB-1656CL)
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: FC, CMCD, ADCC, Activ, Inhib, Depletion
- Human Anti-MS4A1 Recombinant Antibody (TAB-1665CL) (TAB-1665CL)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: CDC
- Human Anti-MS4A1 Recombinant Antibody (TAB-1666CL) (TAB-1666CL)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: CDC
- Human Anti-MS4A1 Recombinant Antibody (TAB-1667CL) (TAB-1667CL)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: CDC
- Human Anti-MS4A1 Recombinant Antibody (TAB-1668CL) (TAB-1668CL)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: CDC
- Human Anti-MS4A1 Recombinant Antibody (TAB-1669CL) (TAB-1669CL)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: CDC
- Human Anti-MS4A1 Recombinant Antibody (TAB-1670CL) (TAB-1670CL)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: CDC
- Human Anti-MS4A1 Recombinant Antibody (TAB-1671CL) (TAB-1671CL)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: CDC
- Anti-Human MS4A1 Recombinant Antibody (hu8E4) (TAB-1672CL)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: Inhib, CDC, ADCC, Apop, FuncS
- Human Anti-MS4A1 Recombinant Antibody (TAB-1674CL) (TAB-1674CL)
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- Application: Cyt, ELISA, FuncS, Inhib
- Human Anti-MS4A1 Recombinant Antibody (TAB-1675CL) (TAB-1675CL)
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- Derivation: Chimeric (murine/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1
- Application: ELISA, WB
- Human Anti-MS4A1 Recombinant Antibody (TAB-1676CL) (TAB-1676CL)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
- Anti-Human MS4A1 Recombinant Antibody (IBI-301) (TAB-1677CL)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: PK
- Human Anti-MS4A1 Recombinant Antibody (TAB-1678CL) (TAB-1678CL)
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- Type: Fully human antibody
- Application: ADCC, CDC
- Human Anti-MS4A1 Recombinant Antibody (TAB-1679CL) (TAB-1679CL)
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- Type: Fully human antibody
- Application: ADCC, CDC
- Human Anti-MS4A1 Recombinant Antibody (TAB-1680CL) (TAB-1680CL)
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- Type: Fully human antibody
- Application: ADCC, CDC
- Human Anti-MS4A1 Recombinant Antibody (TAB-1681CL) (TAB-1681CL)
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- Type: Fully human antibody
- Application: ADCC, CDC
- Human Anti-MS4A1 Recombinant Antibody (TAB-1682CL) (TAB-1682CL)
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- Type: Fully human antibody
- Application: ADCC, CDC
- Human Anti-MS4A1 Recombinant Antibody (TAB-1683CL) (TAB-1683CL)
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- Type: Fully human antibody
- Application: ADCC, CDC
- Human Anti-MS4A1 Recombinant Antibody (TAB-1684CL) (TAB-1684CL)
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- Type: Fully human antibody
- Application: ADCC, CDC
- Human Anti-MS4A1 Recombinant Antibody (TAB-1685CL) (TAB-1685CL)
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- Type: Fully human antibody
- Application: ADCC, CDC
- Human Anti-MS4A1 Recombinant Antibody (TAB-1686CL) (TAB-1686CL)
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- Type: Fully human antibody
- Application: ADCC, CDC
- Human Anti-MS4A1 Recombinant Antibody (TAB-1687CL) (TAB-1687CL)
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- Type: Fully human antibody
- Application: ADCC, CDC
- Human Anti-MS4A1 Recombinant Antibody (TAB-1688CL) (TAB-1688CL)
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- Type: Fully human antibody
- Application: FC, ADCC, CDC, FuncS
- Humanized Anti-Human MS4A1 Recombinant Antibody (TAB-1689CL)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA
- Mouse Anti-MS4A1 Recombinant Antibody (TAB-1657CL) (TAB-1657CL)
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- Application: Apop, FuncS
- Mouse Anti-MS4A1 Recombinant Antibody (TAB-1658CL) (TAB-1658CL)
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- Application: Apop, FuncS
- Mouse Anti-MS4A1 Recombinant Antibody (TAB-1659CL) (TAB-1659CL)
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- Application: Apop, FuncS
- Mouse Anti-MS4A1 Recombinant Antibody (TAB-1660CL) (TAB-1660CL)
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- Application: Apop, FuncS
- Mouse Anti-MS4A1 Recombinant Antibody (TAB-1661CL) (TAB-1661CL)
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- Application: Apop, FuncS
- Mouse Anti-MS4A1 Recombinant Antibody (TAB-1662CL) (TAB-1662CL)
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- Application: Apop, FuncS
- Mouse Anti-MS4A1 Recombinant Antibody (TAB-1663CL) (TAB-1663CL)
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- Application: Apop, FuncS
- Mouse Anti-MS4A1 Recombinant Antibody (TAB-1664CL) (TAB-1664CL)
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- Application: Apop, FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG2a - lambda
- Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab - G2b - kappa
- Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: ELISA, IP, FC, FuncS, IF, Neut
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG2a
- Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1 - kappa
- Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
- Anti-CD20 Antibody-Cytokine Fusion Protein, IgG-RLI (ACFP-SH135)
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- Target: CD20
- Species Reactivity: Human
- Cytokine 1: RLI
- Host: Chimeric (Human-Mouse)
- Cytokine 1 Species: Human
- Molecule Class: L Kappa; IgG2-RLI
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- Target: CD20
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Chimeric (Human-Mouse)
- Cytokine 1 Species: Human
- Molecule Class: scFv-Fc-IL2
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: WB, IF, FuncS
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: WB
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- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: WB, ELISA, FuncS
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, IF, FuncS
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB
- Anti-Human MS4A1 Recombinant Antibody (1F5) (TAB-1632CL)
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- Application: FC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA, FuncS
- Recombinant Anti-human MS4A1 VHH Single Domain Antibody (NAB-913-sdAb)
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- Species Reactivity: Human
- Type: Llama VHH
- Application: IP, FC, ChiP, Neut
- Anti-CD20 (clone hA20)-SN-38 ADC (ADC-125CL)
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- Target: CD20
- Drug: SN-38 (7-ethyl-10-hydroxycamptothecin)
- Anti-CD20 (clone Batl206)-SMCC-MDC ADC (ADC-160CL)
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- Target: CD20
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: MDC (maytansinol)
- Anti-CD20-CL2A-SN-38 ADC (ADC-021LCT)
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- Target: CD20
- Linker: CL2A
- Drug: SN-38 (7-ethyl-10-hydroxycamptothecin)
- Anti-CD20-CL2E-SN-38 ADC (ADC-022LCT)
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- Target: CD20
- Linker: CL2E
- Drug: SN-38 (7-ethyl-10-hydroxycamptothecin)
- Anti-CD20 (1F5)-vcMMAE ADC (ADC-023LCT)
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- Target: CD20
- Linker: VC (valine-citrulline)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-CD20 (rituximab)-vcMMAE ADC (ADC-024LCT)
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- Target: CD20
- Linker: VC (valine-citrulline)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-CD20 (1F5) Fab-HPMA ADC (ADC-025LCT)
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- Target: CD20
- Linker: N-(2-Hydroxypropyl)methacrylamide (HPMA)
- Anti-CD20 (2H7)-mcc-DM1 ADC (ADC-026LCT)
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- Target: CD20
- Linker: mcc (Maleimidomethyl cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- Anti-CD20-SPP-DM1 ADC (ADC-185LZY)
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- Target: CD20
- Linker: SPP (N-succinimidyl-4-(2-pyridyldithio)pentanoate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
- Anti-CD20-MCC-DM1 ADC (ADC-186LZY)
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- Target: CD20
- Linker: MCC (Maleimidomethyl cyclohexane-1-carboxylate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
- Anti-CD20-mc-vc-PABC-MMAE ADC (ADC-187LZY)
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- Target: CD20
- Linker: mc-VC-PABC (maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
- Drug: MMAE (monomethyl auristatin E)
- Anti-CD20-mc-MMAF ADC (ADC-188LZY)
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- Target: CD20
- Linker: mc (maleimidocaproyl)
- Drug: MMAF (monomethyl auristatin F)
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members.

